We analyze a model where the government has to decide whether to impose a lockdown in a country to prevent the spread of a possibly virulent disease. If the government decides to impose a lockdown, it has to determine its intensity, timing and duration. We find that there are two competing effects that push the decision in opposite directions. An early lockdown is beneficial not only to slow down the spread of the disease, but creates beneficial habit formation (such as social distancing, developing hygienic habits) that persists even after the lockdown is lifted. Against this benefit of an early lockdown, there is a cost from loss of information about the virulence and spread of the disease in the population in addition to a direct cost to the economy. Based on the prior probability of the disease being virulent, we characterize the timing, intensity and duration of a lockdown with the above mentioned tradeoffs. Specifically, we show that as the precision of learning goes up, a government tends to delay the imposition of lockdown. Conversely, if the habit formation parameter is very strong, a government is likely to impose an early lockdown.
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http://dx.doi.org/10.1016/j.jmateco.2020.11.008 | DOI Listing |
Proc Natl Acad Sci U S A
March 2025
State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Center for Evolutionary Biology, School of Life Sciences, Department of Liver Surgery and Transplantation Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Positive selection at the 2q21.3 enhancer region for lactase gene () expression in Europeans and Africans has long been attributed to selection for lactase persistence (LP), the capacity of adults to digest lactose in milk, presumably because of the benefits associated with milk consumption. While considered a classic example of gene-culture coevolution, recently doubts have been raised about the link between selection at 2q21.
View Article and Find Full Text PDFPhenomics
December 2024
Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing, 210009 China.
Unlabelled: The TRacing Etiology of Non-communicable Diseases (TREND) cohort is a prospective longitudinal cohort and biobank that is mainly based in Ma'anshan, Anhui Province, China. The primary aim of the study is to decipher comprehensive molecular characterization and deep phenotyping for a broad spectrum of chronic non-communicable diseases (NCDs), which focuses on providing mechanistic insights with diagnostic, prognostic and therapeutic implications. The recruitment was initiated in 2023 and is expected to complete in 2025 with 20,000 participants originated from urban and rural area.
View Article and Find Full Text PDFACS Omega
March 2025
Programa de Pós-Graduação em Biodiversidade e Biotecnologia (REDE BIONORTE), Instituto de Saúde Coletiva (ISCO), Universidade Federal do Oeste do Pará (UFOPA), Rua Vera Paz, s/no., Salé, CEP, 68040-255 Santarém, Pará, Brazil.
Fish farming and artisanal fishing represent important protein sources for riverside communities and populations of small towns in the Amazon. In recent decades, the Amazon basin has been the target of environmental contamination by mercury (Hg), which warns of possible adverse effects of human exposure through food. In this study, we evaluated the effect of mercury bioaccumulation in juvenile tilapia exposed via dietary intake.
View Article and Find Full Text PDFPsychol Health
March 2025
Department of Physical Education, College of Education, Seoul National University, Seoul, Republic of Korea.
Objective: Most university students struggle to translate their intention to engage in physical activity into actual behaviour. While various theories have been proposed to explain physical activity behaviour, most focus on explicit cognitions such as intention. The aim of this study is to apply the Multi-Process Action Control(M-PAC) model to Korean university students, examining the entire process from intention formation to behaviour implementation, while also investigating the predictive utility of the M-PAC framework for explaining physical activity behaviour.
View Article and Find Full Text PDFBiofactors
March 2025
Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.
Chronic exposure to arsenic can lead to various health issues, including cancer. Concerns have been mounting about the enhancement of arsenic toxicity through co-exposure to various prevalent lifestyle habits. Smokeless tobacco (SLT) products are commonly consumed in South Asian countries, where their use frequently co-occurs with exposure to arsenic from contaminated groundwater.
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