AI Article Synopsis

  • A study was conducted to investigate the cardiac effects of COVID-19 in children, as existing literature is limited on this topic despite the widespread infection rate.
  • Seventy hospitalized children with COVID-19 were compared with seventy healthy children, utilizing lab tests, electrocardiography (ECG), and echocardiography (TTE).
  • The study found increased cardiac parameters in COVID-19 patients, including fragmentation in ECG and mild mitral insufficiency in some cases, suggesting that children might also experience significant cardiac effects from the virus, contrary to previous assumptions.

Article Abstract

Background/aim: Approximately 40 million individuals worldwide have been infected with SARS-CoV-2, the virus responsible for the novel coronavirus disease-2019 (COVID-19). Despite the current literature about the cardiac effects of COVID-19 in children, more information is required. We aimed to determine both cardiovascular and arrhythmia assessment via electrocardiographic and echocardiographic parameters.

Materials And Methods: We evaluated seventy children who were hospitalized with COVID-19 infections and seventy children as normal control group through laboratory findings, electrocardiography (ECG), and transthoracic echocardiography (TTE).

Results: We observed significantly increased levels of Tp-Te, Tp-Te/QT, and Tp-Te/QTc compared with the control group. Twenty-five of 70 (35.7%) patients had fragmented QRS (fQRS) without increased troponin levels. On the other hand, none of the patients had pathologic corrected QT(QTc) prolongation during the illness or its treatment. On TTE, 20 patients had mild mitral insufficiency, among whom only five had systolic dysfunction (ejection fraction < 55%). There was no significant difference between the patient and control groups, except for isovolumic relaxation time (IVRT) in terms of mean systolic and diastolic function parameters. IVRT of COVID patients was significantly lower than that of control group.

Conclusion: Despite all the adult studies, the effects of COVID‐19 on myocardial function are not well established in children. The thought that children are less affected by the illness may be a misconception.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283426PMC
http://dx.doi.org/10.3906/sag-2010-240DOI Listing

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