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Classification of reflux patterns in patients with great saphenous vein insufficiency and correlation with clinical severity. | LitMetric

AI Article Synopsis

  • The study aims to create a classification system for reflux patterns related to great saphenous vein insufficiency and examine how these patterns relate to patient demographics and clinical severity.
  • Researchers analyzed data from 503 patients with varicose veins, classifying reflux patterns into four types based on different areas of vein involvement, using Doppler ultrasonography for assessment.
  • Findings showed that the most common reflux pattern was type 3, with patients having type 1 exhibiting younger age, lower BMI, fewer children, and milder clinical severity, while more severe patterns (involving the malleolar region) correlated with increased clinical severity scores.

Article Abstract

Purpose: This study aims to establish a clinically applicable classification of reflux patterns in patients with great saphenous vein insufficiency and to evaluate the relationship between this classification, the demographics, and severity of clinical findings.

Methods: This is a retrospective study from prospectively collected data of 503 patients who had the complaint of varicose vein. All patients had complete physical examination and their medical history was recorded. Lower limbs of all patients were examined with Doppler ultrasonography. A total of 787 limbs with great saphenous vein insufficiency were included in the analysis. The reflux patterns of great saphenous vein insufficiency were classified into 4 types as: type 1, great saphenous vein reflux without involvement of malleolar region and saphenofemoral junction (SFJ); type 2, reflux involving malleolar region with competent SFJ; type 3, reflux involving SFJ with competent malleolar region; and type 4, reflux involving both the SFJ and the malleolar region. We evaluated the association between the classification of great saphenous vein insufficiency and age, sex, body mass index (BMI), disease duration, clinical, etiological, anatomical and pathophysiological elements (CEAP) classification and venous clinical severity score (VCSS).

Results: The mean age of the patients was 45.3±11.7 years, with a male-to-female ratio of 2:3. The most common reflux pattern in patients with great saphenous vein insufficiency was type 3 (48.9%), while 14.8% of patients had type 1, 10.4% had type 2, and 25.7% had type 4. Patients with type I reflux pattern were younger in age (p = 0.002), had lower BMI (p = 0.002), fewer number of children (p = 0.008), as well as milder clinical severity score (p = 0.002) compared to other reflux types. Duration of disease symptoms was not significantly correlated with the reflux patterns, but VCSS increased with the involvement of malleolar region as in type 2 compared to type 1 (2.82±1.67 vs. 2.74±2.31), and further increased with the involvement of SFJ as in type 3 (4.13±2.92 vs. 2.82±1.67). Patients with diffuse reflux pattern (type 4) had the most severe clinical presentation (4.59±2.9).

Conclusion: We developed a clinically applicable classification of reflux patterns in patients with great saphenous vein insufficiency based on the involvement of malleolar region and/or SFJ. We showed an association between weight, BMI, VCSS, CEAP classification and the extent of insufficiency.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963375PMC
http://dx.doi.org/10.5152/dir.2021.19580DOI Listing

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