Symbiotic integration of bioprocesses to design a self-sustainable life supporting ecosystem in a circular economy framework.

Climate change, resource depletion and unsustainable crop productivity are major challenges that mankind is currently facing. Natural ecosystems of earth's biosphere are becoming vulnerable and there is a need to design Bioregenerative Life Support Systems (BLSS) which are ecologically engineered microcosms that could effectively deal with problems associated with urbanization and industrialization in a sustainable manner. The principles of BLSS could be integrated with waste fed biorefineries and solar energy to create a self-sustainable bioregenerative ecosystem (SSBE). Such engineered ecosystems will have potential to fulfil urban life essentials and climate change mitigation thus generating ecologically smart and resilient communities which can strengthen the global economy. This article provides a detailed overview on SSBE framework and its improvement in the contemporary era to achieve circular bioeconomy by means of effective resource recycling.