Spark gap switches are used in various high-power pulse systems because they can quickly transfer the energy stored in the capacitor to the load. A rotary trigger double spark gap (RTDSG) switch is proposed in this paper as a type of switch capable of high repetition at high power. It was found that a pulse switching of 20 kV and 1 kHz was possible by applying the multiple RTDSG switches to increase the repetition rate of the switch. In addition to the basic operating principle of the RTDSG, the effects of switching-related parameters on the operating frequency of the switch were analyzed. As an example of promising applications of the high repetition RTDSG, the generation of shock waves by underwater discharge and the effective dispersion of carbon nanotubes using the shock waves are reported.
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http://dx.doi.org/10.1063/5.0023652 | DOI Listing |
Mol Cancer
December 2024
Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China.
cGAS-STING pathway stands at the forefront of innate immunity and plays a critical role in regulating adaptive immune responses, making it as a key orchestrator of anti-tumor immunity. Despite the great potential, clinical outcomes with cGAS-STING activators have been disappointing due to their unfavorable in vivo fate, signaling an urgent need for innovative solutions to bridge the gap in clinical translation. Recent advancements in nanotechnology have propelled cGAS-STING-targeting nanomedicines to the cutting-edge of cancer therapy, leveraging precise drug delivery systems and multifunctional platforms to achieve remarkable region-specific biodistribution and potent therapeutic efficacy.
View Article and Find Full Text PDFJ Prof Nurs
December 2024
University of Alabama at Birmingham, School of Nursing, 1701 University Blvd, Birmingham, AL 35294, USA. Electronic address:
Background: Academic nurse leadership is associated with nurse faculty job satisfaction, yet there is a gap between theoretical understanding of leadership concepts and specific actionable behaviors that can be implemented to increase nurse faculty job satisfaction.
Purpose: The purpose of this study was to create an evidence-based action guide for academic nurse leaders at all leadership levels to use to improve nurse faculty job satisfaction.
Methods: A two-phase approach was used.
Heliyon
November 2024
Department of Medical Oncology, The Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, 650101, Yunnan, China.
Data Brief
December 2024
USDA-ARS Invasive Insect Biocontrol and Behavior Laboratory, Beltsville, MD 20705, United States.
Nano Converg
November 2024
Radiation Laboratory, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
Lead halide perovskites have emerged as a new class of semiconductor materials with exceptional optoelectronic properties, sparking significant research interest in photovoltaics and light-emitting diodes. However, achieving long-term operational stability remains a critical hurdle. The soft, ionic nature of the halide perovskite lattice renders them vulnerable to various instabilities.
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