Objectives And Background: In this study we assessed the prognostic value of main pulmonary artery diameter and its ratio to ascending aorta diameter (P/Ao ratio) in advanced heart failure patients.
Methods: Patients with advanced heart failure who were candidates for heart transplantation were retrospectively evaluated. The clinical information, cardiac catheterisation results, and computed tomography images were gathered from institutional database system. The observed and predicted probabilities for survival were analysed in a nomogram.
Results: The P/Ao ratio was found to be a strong predictor for MACE both in traditional multivariable Cox proportional hazard regression modelling (increase in P/Ao ratio per 2 SD, HR:2.72, 95% CI 1.14-6.48, = 0.024) and ridge regression analysis (increase in P/Ao ratio per 2SD, HR:3.45, 95% CI 1.53-7.74, = 0.003). Prediction model showed statistically significant correlation between the observed and predicted probabilities for 1-year survival.
Conclusion: In patients with advanced heart failure, computed tomography derived P/Ao ratio might be a prognostic predictor during follow up.
Background: Recruitment maneuvers are used in patients with ARDS to enhance oxygenation and lung mechanics. Heterogeneous lung and chest-wall mechanics lead to unpredictable transpulmonary pressures and could impact recruitment maneuver success. Tailoring care based on individualized transpulmonary pressure might optimize recruitment, preventing overdistention.
Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy; and Department of Anesthesia and Intensive Care Medicine, Niguarda Ca' Granda, Milan, Italy.
Background: The use of prone position (PP) has been widespread during the COVID-19 pandemic. Whereas it has demonstrated benefits, including improved oxygenation and lung aeration, the factors influencing the response in terms of gas exchange to PP remain unclear. In particular, the association between baseline quantitative computed tomography (CT) scan results and gas exchange response to PP in invasively ventilated subjects with COVID-19 ARDS is unknown.
Pancreatic thickness is an indicator for evaluating pancreatic diseases. The transverse and cross-sectional pancreatic thickness observed on computed tomography (CT) may differ. This study aimed to provide a normal reference range for pancreatic thickness on the transverse plane based on body weight (BW) and assess pancreatic thickness to aorta (P/Ao) ratio.
This study looked at whether lying on your stomach (prone positioning) helps people with mild COVID-19 who are breathing on their own, compared to just receiving regular care.
Out of 61 patients, those who lay on their stomach had a higher chance of needing more help with breathing or dying than those who only received standard care.
In the end, the researchers found that lying on your stomach didn’t help patients recover faster or get out of the hospital sooner.
Background: This study aimed to compare ventilatory parameters recorded in the first days of acute respiratory distress syndrome (ARDS) and mortality at day 60 between coronavirus disease 2019 (COVID-19) and influenza ARDS patients with arterial oxygen tension ( )/inspiratory oxygen fraction ( ) ≤150 mmHg.
Methods: We compared 244 COVID-19 ARDS patients with 106 influenza ARDS patients. Driving pressure, respiratory system compliance ( ), ventilator ratio, corrected minute ventilation (') and surrogate of mechanical power (index=(4×driving pressure)+respiratory rate) were calculated from day 1 to day 5 of ARDS.
