Background: Previous studies have suggested that exposure to air pollution may increase stroke risk, but the results remain inconsistent. Evidence of more recent studies is highly warranted, especially gas air pollutants.
Methods: We searched PubMed, Embase, and Web of Science to identify studies till February 2020 and conducted a meta-analysis on the association between air pollution (PM, particulate matter with aerodynamic diameter less than 2.5 μm; PM, particulate matter with aerodynamic diameter less than 10 μm; NO, nitrogen dioxide; SO, sulfur dioxide; CO, carbon monoxide; O, ozone) and stroke (hospital admission, incidence, and mortality). Fixed- or random-effects model was used to calculate pooled odds ratios (OR)/hazard ratio (HR) and their 95% confidence intervals (CI) for a 10 μg/m increase in air pollutant concentration.
Results: A total of 68 studies conducted from more than 23 million participants were included in our meta-analysis. Meta-analyses showed significant associations of all six air pollutants and stroke hospital admission (e.g., PM: OR = 1.008 (95% CI 1.005, 1.011); NO: OR = 1.023 (95% CI 1.015, 1.030), per 10 μg/m increases in air pollutant concentration). Exposure to PM, SO, and NO was associated with increased risks of stroke incidence (PM: HR = 1.048 (95% CI 1.020, 1.076); SO: HR = 1.002 (95% CI 1.000, 1.003); NO: HR = 1.002 (95% CI 1.000, 1.003), respectively). However, no significant differences were found in associations of PM, CO, O, and stroke incidence. Except for CO and O, we found that higher level of air pollution (PM, PM, SO, and NO) exposure was associated with higher stroke mortality (e.g., PM: OR = 1.006 (95% CI 1.003, 1.010), SO: OR = 1.006 (95% CI 1.005, 1.008).
Conclusions: Exposure to air pollution was positively associated with an increased risk of stroke hospital admission (PM, PM, SO, NO, CO, and O), incidence (PM, SO, and NO), and mortality (PM, PM, SO, and NO). Our study would provide a more comprehensive evidence of air pollution and stroke, especially SO and NO.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839211 | PMC |
| http://dx.doi.org/10.1186/s12199-021-00937-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Biomarkers and Social Determinants in atherosclerotic Arterial Diseases: A Scoping Review.
Ann Vasc Surg
January 2025
Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy; Interuniversity Center of Phlebolymphology (CIFL), "Magna Graecia" University, 88100 Catanzaro, Italy. Electronic address:
Background: Arterial diseases like coronary artery disease, carotid stenosis, peripheral artery disease, and abdominal aortic aneurysm have high morbidity and mortality, making them key research areas. Their multifactorial nature complicates patient treatment and prevention. Biomarkers offer insights into the biochemical and molecular processes, while social factors also significantly impact patients' health and quality of life.
View Article and Find Full Text PDFLong-term exposure to air pollution and greenness in association with respiratory emergency room visits and hospitalizations: The Life-GAP project.
Environ Res
January 2025
Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Background: Air pollution has been linked to respiratory diseases, while the effects of greenness remain inconclusive.
Objective: We investigated the associations between exposure to particulate matter (PM and PM), black carbon (BC), nitrogen dioxide (NO), ozone (O), and greenness (normalized difference vegetation index, NDVI) with respiratory emergency room visits and hospitalizations across seven Northern European centers in the European Community Respiratory Health Survey (ECRHS) study.
Methods: We used modified mixed-effects Poisson regression to analyze associations of exposure in 1990, 2000 and mean exposure 1990-2000 with respiratory outcomes recorded duing ECRHS phases II and III.
Preterm Births Attributable to Criteria Air Pollutant Exposure in Bangladesh During 2015-2019.
Environ Pollut
January 2025
Department of Civil Engineering, Khulna University of Engineering & Technology, Khulna, 9203, Bangladesh; Department of Civil Engineering, University of Creative Technology Chittagong, Chattogram, 4212, Bangladesh.
Criteria air pollutant exposure impacts human health through various pathways. Preterm birth (PTB) is one of the major adverse birth outcomes (ABO) associated with such exposure. Although numerous global and regional studies have been conducted on this issue, few have recently investigated the impact of major criteria air pollutant exposure on PTBs in Bangladesh, one of the world's most polluted countries with the highest relative PTB rate.
View Article and Find Full Text PDFUnderestimated Industrial Ammonia Emission in China Uncovered by Material Flow Analysis.
Environ Pollut
January 2025
State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing 210023, China; Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing, 210044, China. Electronic address:
Ammonia (NH) is crucial in fine particulate matter (PM) formation, but past estimations on industrial NH emissions remain highly uncertain. In this study, the flow of NH within air pollution control devices (APCDs) were investigated basing on material flow analysis with in-situ measurements of NH concentrations at the inlets and outlets of each APCD. Then, by combing emission factors updated with recent in-situ measurements and provincial-level activity data from statistical yearbooks and associated reports, NH emissions from various industrial sources, as well as their spatial distribution across China in 2020, were evaluated.
View Article and Find Full Text PDFThe synergies of air quality monitoring program: Information disclosure and pollution control.
J Environ Manage
January 2025
Chongqing Environmental Consulting Co., Ltd., CISDI Group Co., Ltd., Chongqing, China. Electronic address:
To deal with the increasingly severe climate crisis and environmental pollution, China launched a nationwide real-time air quality monitoring program in three batches, a milestone moment in its environmental governance history. Using the time-varying difference-in-differences model, this study explores the synergies of this program across 284 cities from 2009 to 2019. The findings are as follows: (1) With environmental information disclosed, the national air quality monitoring program can reduce the outdoor fine particulate matter concentration by an overall effect of 3.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!