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The Effects of Silymarin on Calcium Chloride-Induced Arrhythmia in Male Rat.
Oxid Med Cell Longev
September 2024
Department of Basic Sciences School of Veterinary Medicine Shiraz University, Shiraz, Iran.
Antioxidants play an important role in protecting cardiac arrhythmias. Silymarin, strong antioxidant, is effective in reducing the complications caused by arrhythmias. This study was conducted to determine the effect of silymarin on the prevention and treatment of calcium chloride-induced arrhythmia.
View Article and Find Full Text PDFLong QT Syndrome With Drugs Used in the Management of Arrhythmias: A Systematic Review.
Cureus
July 2024
General Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Long QT syndrome (LQTS) is a severe cardiac disorder characterized by an abnormally prolonged QTc interval on an electrocardiogram (ECG), which can result in life-threatening irregular heart rhythms. The use of certain medications, particularly anti-arrhythmic drugs such as quinidine, sotalol, and amiodarone, can lead to acquired LQTS by prolonging the QT interval through the inhibition of specific ion channels responsible for heart repolarization, which may present symptoms like fainting, seizures, and sudden cardiac arrest. This systematic review, conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, focused on analyzing the association between Long QT syndrome and drugs utilized for managing arrhythmias, involving a thorough examination of six selected studies from an initial pool of 68 articles.
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