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Loxosceles reclusa Envenomation Causing Acute Hemolytic Anemia: A Case Report on Loxoscelism.
Cureus
July 2024
Department of Emergency Medicine, Ascension Health, Murfreesboro, USA.
Article Synopsis
- The case report aims to educate about the signs, assessment, diagnosis, and management of envenomation, specifically focusing on loxoscelism*.
- It presents a specific case of an adult who suffered from loxoscelism and ended up in the emergency department for care*.
- Additionally, the report seeks to contribute to existing literature by including bite wound images linked to loxoscelism that required hospital admission and treatment for acute hemolytic anemia*.
Novel insights into the application of recombinant mutated phospholipases D as antigens for developing new strategies against Loxoscelism.
Acta Trop
October 2024
Department of Cell Biology, Federal University of Paraná (UFPR), Curitiba, 81530-900, PR, Brazil. Electronic address:
Loxoscelism is the pathological condition triggered by a brown spider bite. The venom of these spiders is rich in phospholipases D (PLDs), which can induce virtually all local and systemic manifestations. Recombinant mutated PLDs from clinically relevant Loxosceles species in South America have been investigated as potential antigens to develop novel therapeutic strategies for loxoscelism.
View Article and Find Full Text PDFNecrotic ulcers caused by Loxosceles rufescens bites: a report of seven patients and scanning electron microscopy of the spider.
Eur J Dermatol
June 2024
SC Dermatologia, Fondazione IRCCS, Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Article Synopsis
- Loxosceles rufescens is a spider that can cause bites leading to necrotic ulcers in humans; the study documents twelve cases with confirmed bites and provides detailed clinical observations.
- Seven patients developed single necrotic ulcers in various body parts, experiencing pain and burning but showing no systemic symptoms; they were treated with topical solutions and some needed antibiotics for bacterial infections.
- Recovery took up to eight weeks for all patients, but five developed scars, highlighting the need for proper identification of the spider to confirm the bite's causative agent and manage treatment effectively.
Systemic loxoscelism leading to autoimmune haemolytic anaemia in a healthy young adult.
BMJ Case Rep
July 2024
Infectious Disease, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
The brown recluse spider () is endemic to the southcentral Midwest and the Southern United States. A bite from a brown recluse spider may result in symptoms that range from local skin necrosis to systemic complications such as acute haemolytic anaemia, disseminated intravascular coagulopathy, rhabdomyolysis and death. Although rare, systemic loxoscelism is a clinical diagnosis of exclusion that should be considered in a patient with acute autoimmune haemolytic anaemia.
View Article and Find Full Text PDFA brown recluse spider bite wound: a case report and literature review.
J Wound Care
July 2024
University of Toledo, College of Medicine and Life Sciences, Department of Surgery, Toledo, Ohio, US.
The authors have no conflicts of interest.
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