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Case Report: Loeffler endocarditis as a cause of left ventricular thrombosis in young women: a case study and literature review.
Front Cardiovasc Med
December 2024
Department of Cardiology, The First Affiliated Hospital of Shandong First Medical University, Shandong First Medical University, Shandong, China.
It is unusual for young patients without any underlying diseases to experience sudden cerebral infarction and heart failure. Here, we report a rare case of a 28-year-old female patient who presented with chest tightness and dizziness. Left ventricular thrombus formation and cardiac insufficiency were evident on echocardiogram, while multiple acute or subacute cerebral infarctions were visible on brain magnetic resonance imaging.
View Article and Find Full Text PDFMyositis/myasthenia gravis caused by immune checkpoint inhibition: A report of two cases and a brief review of the literature.
Med Int (Lond)
December 2024
Department of Neurology, University of Alabama, Birmingham, AL 35294, USA.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by enhancing the ability of the immune system to combat malignancies. Nivolumab and cemiplimab, monoclonal antibodies targeting programmed cell death protein 1, have exhibited notable therapeutic efficacy; however, they are associated with immune-related adverse events (irAEs). The present study describes the cases of 2 patients, a 71-year-old male with metastatic esophageal adenocarcinoma and a 66-year-old female with metastatic squamous cell carcinoma who developed acute/subacute onset rapidly progressive myositis/myasthenia gravis (MG) following treatment with nivolumab and cemiplimab.
View Article and Find Full Text PDFCase report: Intravascular large B cell lymphoma mimicking acute demyelinating encephalomyelitis after SARS-CoV-2 reinfection: diagnostic value of advanced MRI techniques and the literature review with the assistance of ChatGPT.
Front Immunol
November 2024
Department of Radiology, The Affiliated Yuebei People's Hospital of Shantou University Medical College, Shaoguan, Guangdong, China.
The intravascular large B cell lymphoma (IVLBCL) is a rare subtype of lymphoma. The IVBCL is usually found with systemic involvement, with a relative predilection for skin and the central nervous system (CNS), followed by a rapidly progressive course and poor prognosis with a high mortality rate. IVLBCL is difficult to diagnose based on conventional MRI alone.
View Article and Find Full Text PDFAn immunohistochemical study on the evaluation of mast cell, interleukin 17 and interleukin 1β profile in contagious caprine pleuropneumonia.
Vet Res Forum
October 2024
Department of Pathology, Faculty of Veterinary Medicine, Aksaray University, Aksaray, Türkiye.
Article Synopsis
- Contagious caprine pleuropneumonia (CCPP) is a serious and rapidly spreading disease in goats, causing significant economic losses in Asia, Africa, and the Middle East.* -
- The study examined lung tissues from 40 goats with CCPP and 6 healthy controls to analyze the role of mast cells and the proteins IL-17 and IL-1β during different inflammation stages (peracute-acute vs. subacute-chronic).* -
- Findings showed increased mast cell numbers and levels of IL-17 and IL-1β during the peracute-acute phase compared to controls, while these levels decreased in the subacute-chronic phase, highlighting their importance in the disease's progression.*
Nitrous oxide abuse and associated neurological diseases.
BMC Neurol
November 2024
Chulabhorn International College of Medicine, Thammasat University, Bangkok, Thailand.
Article Synopsis
- Nitrous oxide, commonly used as an anesthetic, is increasingly abused recreationally, leading to neurological issues in users.
- A study reviewed seven patients aged 19-32 who inhaled nitrous oxide and subsequently experienced ataxia and sensory dysfunction, with some showing coexisting encephalopathy.
- Although patients had poor short-term outcomes, most showed significant recovery after more than six months, indicating potential long-term improvement despite initial symptoms.
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