AI Article Synopsis
- - The diagnosis of coagulopathy (disorders related to blood clotting) in kids can be tough, and both congenital (present at birth) and acquired types need careful testing and management.
- - Hospitalized children often have acquired coagulopathies, which require specific coagulation tests to guide their treatment as the incidence of thrombosis (blood clots) in kids is on the rise.
- - For immediate treatment of identified thrombus, therapeutic anticoagulation is started, with the choice of anticoagulant influenced by the child's health status; however, thrombophilia testing is unreliable during acute illnesses.
Article Abstract
The diagnosis of coagulopathy or thrombophilia in pediatric patients can be challenging. Congenital coagulopathies often present in the pediatric period and require appropriate work-up for diagnosis and ongoing management. Acquired coagulopathies of childhood are frequently encountered in hospitalized children and warrant appropriate coagulation testing for goal-directed therapy. The incidence of thrombosis is increasing in pediatric patients. After identifying the presence of thrombus, acute management includes initiating therapeutic anticoagulation. Choice of anticoagulant depends on patient's clinical status, along with availability of the anticoagulant. Thrombophilia evaluation is performed when children present with spontaneous thrombosis. Thrombophilia tests are inaccurate during acute illness.
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| http://dx.doi.org/10.1016/j.cll.2020.10.006 | DOI Listing |
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