Cortisol-Producing Adrenal Adenomas With Intense Activity on 68Ga-Pentixafor PET/CT.

Clin Nucl Med

From the Department of Nuclear Medicine and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine.

Published: April 2021

CXC chemokine receptor type 4 as a G-protein-coupled receptor has been confirmed to be highly expressed in functional adrenocortical adenomas. 68Ga-pentixafor, a CXC chemokine receptor type 4-specific ligand, has been reported as a promising tracer to evaluate functional nature of adrenal adenomas. We report intense 68Ga-pentixafor activity of cortisol-producing adrenal adenomas in 2 patients with adrenocorticotropic hormone-independent Cushing syndrome.

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Source
http://dx.doi.org/10.1097/RLU.0000000000003503DOI Listing

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