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The impact of pneumoperitoneum on esophagogastric junction distensibility during anti-reflux surgery. | LitMetric

The impact of pneumoperitoneum on esophagogastric junction distensibility during anti-reflux surgery.

Surg Endosc

Division of Endocrine and Minimally Invasive Surgery, Department of Surgery, New York-Presbyterian Hospital, Weill Cornell Medical College, 525 East 68th Street, K-836, New York, NY, 10065, USA.

Published: January 2022

AI Article Synopsis

  • The study aimed to evaluate how pneumoperitoneum (a gas-filled abdominal state) affects the compliance of the esophagogastric junction (EGJ) during anti-reflux surgery, using EndoFLIP® to measure dynamic compliance changes.
  • Results showed that at 15 mmHg of pneumoperitoneum, there were significant differences in pressure and distensibility index (DI) measurements, but no significant differences at 10 mmHg.
  • The findings suggest that pneumoperitoneum impacts EGJ compliance, particularly at higher pressures, and these variations should be considered in clinical practices and guidelines for surgical procedures.

Article Abstract

Objective: We aimed to quantify the contribution of pneumoperitoneum on compliance of the esophagogastric junction (EGJ) during anti-reflux surgery.

Background: Compliance of the EGJ is reduced with anti-reflux surgery. EndoFLIP® planimetry can be used to assess dynamic changes of EGJ compliance intraoperatively. It is unclear how pneumoperitoneum impacts intraoperative measurements by EndoFLIP® and the implications thereof on validity of the results. Therefore, determining variability in EndoFLIP® measurements based on pneumoperitoneum is warranted to establish guidelines to interpret clinical outcomes.

Methods: Primary anti-reflux surgery was performed on 39 consecutive patients with pathologic reflux. Intraoperative EGJ measurements including distensibility index (DI), cross-sectional area (CSA), and intrabag pressure were collected using EndoFLIP® at 0, 10, and 15 mmHg of intraperitoneal pressure. Data were acquired pre-procedure, post-hiatal hernia repair, and post-LES augmentation with fundoplications.

Results: Patients underwent Nissen (13.2%), Toupet (68.4%), LINX (10.5%), or Hill-fundoplications (7.9%). There was no difference between 0 and 10 mmHg of pneumoperitoneum in CSA, pressure, or DI measurements pre-procedure; however, there was a difference between 0 and 15 mmHg in pressure (p = 0.016) and DI (p = 0.023) measurements. After LES augmentation, 10 mmHg intraperitoneal pressure reduced DI, though the absolute difference is small (2.0 vs. 1.5 mm/mmHg, p = 0.002).

Conclusion: Pneumoperitoneum affected EGJ distensibility at 15 mmHg, but not 10 mmHg, of insufflation prior to anti-reflux procedures. After anti-reflux surgery, there was a significant variance between 0 and 10 mmHg of pneumoperitoneum in pressure and distensibility. The change in pressure appears linear and needs to be considered if procedural modifications are performed based on intraoperative findings and when evaluating clinical outcomes.

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Source
http://dx.doi.org/10.1007/s00464-021-08291-7DOI Listing

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