[Tridimensional in vitro models of nervous and immune systems in the skin].

Med Sci (Paris)

Laboratoire CNRS UPR3572 / I2CT Immunologie, immunopathologie et chimie thérapeutique, Université de Strasbourg, Institut de biologie moléculaire et cellulaire, 2 allée Konrad Roentgen, 67084 Strasbourg, France.

Published: January 2021

The immune system and the sensory nervous system are responsible for perceiving danger under distinct yet complementary forms. In the last few years, neuroimmune interactions have become an important topic of dermatological research for conditions including wound healing, atopic dermatitis and psoriasis. We present here a selection of tridimensional in vitro models that reproduce skin structure and integrate an immune or a sensory function. Future evolutions of such models are expected to greatly contribute in a better understanding of reciprocal influences between sensory nervous system and immune system.

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Source
http://dx.doi.org/10.1051/medsci/2020260DOI Listing

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