AI Article Synopsis
- - In 2018, the estimated prevalence of chlamydia among U.S. individuals aged 15 to 39 was 2.35 million, with about 3.98 million new cases, while gonorrhea prevalence was around 209,000, with 1.57 million new cases reported.
- - A significant portion of gonorrhea cases, approximately 804,000 newly acquired infections, displayed antimicrobial resistance, highlighting concerns about treatment efficacy.
- - This data, collected from various health surveys and mathematical models, indicates a notable increase in the burden of these sexually transmitted infections since the last estimates in 2008.
Article Abstract
Background: The most recent prevalence and incidence estimates for chlamydia and gonorrhea, the 2 most reported sexually transmitted infections in the United States, were for 2008. We present updated estimates of the number of prevalent and incident chlamydial and gonococcal infections for 2018.
Methods: We estimated chlamydial prevalence directly from the 2015 to 2018 cycles of the National Health and Nutrition Examination Survey and chlamydial incidence using a mathematical model primarily informed by National Health and Nutrition Examination Survey and case report data. Total and antimicrobial-resistant gonococcal prevalence and incidence were estimated using mathematical models primarily informed by case report and Gonococcal Isolate Surveillance Program data. Estimates were calculated for the total population, all women, and all men aged 15 to 39 years, stratified by age group. Primary estimates represent medians and uncertainty intervals represent the 25th (Q1) and 75th (Q3) percentiles of the empirical frequency distributions of prevalence and incidence for each infection.
Results: Among persons aged 15 to 39 years in the United States in 2018, we estimate 2.35 (Q1, 2.20; Q3, 2.51) million prevalent and 3.98 (Q1, 3.77; Q3, 4.22) million incident chlamydial infections, and an estimated 209,000 (Q1, 183,000; Q3, 241,000) prevalent and 1.57 (Q1, 1.44; Q3, 1.72) million incident gonococcal infections. Of all gonococcal infections, there were 107,000 (Q1, 94,000; Q3, 124,000) prevalent and 804,000 (Q1, 738,000; Q3, 883,000) incident infections demonstrating antimicrobial resistance or elevated minimum inhibitory concentrations to selected antibiotics.
Conclusions: Chlamydia and gonorrhea were very common in the United States in 2018. Estimates show that more than 800,000 newly acquired gonococcal infections in 2018 demonstrated resistance or elevated minimum inhibitory concentrations to currently or previously recommended antibiotics.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153658 | PMC |
| http://dx.doi.org/10.1097/OLQ.0000000000001382 | DOI Listing |
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