Benzothiazolium salts as reagents for the deoxygenative perfluoroalkylthiolation of alcohols.

Beilstein J Org Chem

Institute of Chemistry and Biochemistry, Freie Universität Berlin, Fabeckstrasse 34-36, 14195 Berlin, Germany.

Published: January 2021

A series of 2-(perfluoroalkylthio)benzothiazolium (BT-SR) salts have been synthesized that serve as convenient sources of hitherto underexplored perfluoroalkylthiolate anions. An investigation of their reactivity in a deoxygenative nucleophilic substitution reaction led to the development of an unprecedented process that provides pentafluoroethyl and heptafluoropropyl thioethers directly from readily available alcohols.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801780PMC
http://dx.doi.org/10.3762/bjoc.17.8DOI Listing

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