Thomas Merton's vision of the original unity of humankind speaks of the oneness of the inner life of the Trinity. It is a vision that we need and one that the healers among us can offer us, whether they are acting as doctors or simply as Christians.
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| http://dx.doi.org/10.1177/0024363920974836 | DOI Listing |
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Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (the PROMIZING study): update to the statistical analysis plan for a randomized controlled trial.
Trials
December 2024
Department of Critical Care, Keenan Research Centre, St Michael's Hospital, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.
Background: We previously published the protocol and statistical analysis plan for a randomized controlled trial of Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: the PROMIZING study in Trials ( https://doi.org/10.1186/s13063-023-07163-w ).
View Article and Find Full Text PDFExploring Sex, Gender, and Gender-Related Sociocultural Factors in Clinical Decision-Making for Older Adults Using a Prescribing Cascade Vignette: A Transnational Qualitative Study.
Drugs Aging
December 2024
Women's Age Lab, Women's College Hospital, Toronto, ON, Canada.
Background: Despite growing awareness of sex differences in inappropriate prescribing among older adults, including the initiation of problematic prescribing cascades, the impact of gender bias remains largely unexplored.
Objectives: We explored how a patient's sex and gender-related sociocultural factors influence physicians' prescribing decisions, potentially leading to prescribing cascades in older adults. A secondary objective was to explore whether and how physician sex affected prescribing decisions for female and male patients.
Culturally-aligned clinical leadership competencies for effective teamwork in Japanese healthcare.
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November 2024
Center for Medical Education and Career Development, Fukushima Medical University, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan.
Background: Clinical leadership competencies for effective teamwork differ between Western cultures, where an independent self-construal prevails, and Japanese society, where the self-construal is rooted in interdependence. Although 27 out of 82 Japanese medical schools have 'leadership' as an educational outcome, specific competencies are poorly described, hindering the development of contextually-relevant leadership education. This study aimed to identify clinical leadership competencies and articulate the attributes and skills fundamental to leadership as perceived by Japanese physicians.
View Article and Find Full Text PDFIn vivo characterization of ACE2 expression in Sprague-Dawley rats and cultured primary brain pericytes highlights the utility of Rattus norvegicus in the study of COVID-19 brain pathophysiology.
Brain Res
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St. Michael's Hospital, Unity Health Toronto, Toronto, ON Canada; Institute of Medical Science and the Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada.
A high number of COVID-19 patients report ongoing neurological impairments including headache, fatigue and memory impairments. Our understanding of COVID-19 disease mechanisms in the brain is limited and relies on post-mortem human tissues, in vitro studies in various cell lines (both human and animal) as well as preclinical studies in a variety of species. Notably the use of rats in the study of COVID-19 has been scarce in part due to early reports of low infectivity of the original Wuhan strain in mice and rats.
View Article and Find Full Text PDFPaper 3: a systematic review of definitions for "racial health equity" and related terms within health-related articles.
J Clin Epidemiol
December 2024
Center for Optimal Aging, Marymount University, Arlington, VA, USA. Electronic address:
Objectives: To systematically evaluate definitions of "racial health equity" (RHE) and related terms within health-related academic literature.
Study Design And Setting: We systematically evaluated definitions of RHE and related terms within health-related academic articles. Articles published in English were included, and no date restrictions were imposed.
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