AI Article Synopsis
- The study evaluated the effectiveness of a deproteinized bovine bone mineral combined with collagen and hyaluronic acid for preserving bone structure in extraction sites.
- After extracting teeth from animal models, various treatments were applied, including collagen sponges and bone preservation methods, to assess their impact after 1 and 3 months.
- Results showed that the combination of DBBM-C with hyaluronic acid significantly maintained ridge width and enhanced bone formation compared to other treatments, indicating its potential for better outcomes in dental procedures.
Article Abstract
Background: The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM-C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets.
Methods: Bilateral third, fourth premolars and first molar were hemisected, distal roots were extracted, and then combined endodontic periodontal lesion was induced in the remaining mesial roots. After 4 months, the mesial roots were extracted and the following four treatments were randomly performed: Absorbable collagen sponge (ACS), ACS soaked with HA (ACS+HA), ridge preservation with DBBM-C covered with a collagen membrane (RP), ridge preservation with DBBM-C mixed with HA and covered with a collagen membrane (RP+HA). Animals were sacrificed at 1 and 3 months following treatment. Ridge dimensional changes and bone formation were examined using microcomputed tomography, histology, and histomorphometry.
Results: At 1 month, ridge width was significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups, while the highest proportion of mineralized bone was observed in ACS+HA group. At 3 months, ridge width remained significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups. ACS+HA and RP+HA treatments featured the highest proportion of mineralized bone and bone volume density compared with the other groups. No statistical difference was observed between ACS+HA and RP+HA treatments.
Conclusions: Ridge preservation with the mixture DBBM-C/HA prevented dimensional shrinkage and improved bone formation in compromised extraction sockets at 1 and 3 months.
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| http://dx.doi.org/10.1002/JPER.20-0832 | DOI Listing |
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