Mobile health (mHealth) technology can circumvent barriers to participation in weight loss programs faced by new mothers. The objective of this study was to assess weight change and program engagement in postpartum women ( = 130) participating in a 24-week behavior change mHealth weight-loss intervention. Participants were recruited through a program offered on a commercial mHealth application that provided evidence-based lifestyle interventions. To meet inclusion criteria, women had to be 18-45 years of age, and given birth within 2 years before the start of the study. Participants signed up for the Noom Healthy Weight program between January and March of 2019 and were offered the program free of charge. Linear mixed models were conducted; the primary outcome was weight change from baseline at 16 and 24 weeks. Secondary outcomes were program engagement and their relationship with completion status. Results showed that time was a significant predictor of weight at week 16 [(-3.94) = -9.40; < 0.001] and week 24 [(-4.08) = -9.74; < 0.001]; users lost 3.94 kgs at week 16 and 4.08 kgs at week 24, compared with baseline. In addition, body mass index significantly decreased at week 24 [(112) = 7.33, < 0.0001] with the majority of participants (80%) experiencing reductions by more than 2 units. On average, subjects who completed the program (completers) lost more weight compared with those who did not complete the program [(-5.09) = -2.94; = 0.004], losing 5.09 kgs (95% CI -8.48 to -1.69) throughout the 24 weeks. This cohort study shows that a uniquely mobile, behavior change intervention for weight management is effective at producing significant weight loss with potential to address postpartum weight retention.
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http://dx.doi.org/10.1089/jwh.2020.8584 | DOI Listing |
Drug Saf
January 2025
Department of Public Health Pharmacy and Management, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Introduction: The COVID-19 pandemic accelerated new vaccine development. Limited safety data necessitated robust global safety surveillance to accurately identify and promptly communicate potential safety issues. The African Union Smart Safety Surveillance (AU-3S) program established the Joint Signal Management (JSM) group to support identification of potential vaccine safety concerns in five pilot countries (Ethiopia, Ghana, Kenya, Nigeria, South Africa), accounting for approximately 35% of the African population.
View Article and Find Full Text PDFNat Commun
January 2025
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
While animals readily adjust their behavior to adapt to relevant changes in the environment, the neural pathways enabling these changes remain largely unknown. Here, using multiphoton imaging, we investigate whether feedback from the piriform cortex to the olfactory bulb supports such behavioral flexibility. To this end, we engage head-fixed male mice in a multimodal rule-reversal task guided by olfactory and auditory cues.
View Article and Find Full Text PDFChronic obstructive pulmonary disease (COPD) is a collection of conditions that cause permanent damage to the lungs. Among a range of treatment options, patients can benefit from pulmonary rehabilitation (PR) programmes involving physical exercises and education.The risk of developing COPD is higher for substance misusers than the general population.
View Article and Find Full Text PDFJ Physiol Sci
January 2025
Department of Neurology, Keio University School of Medicine, Tokyo, Japan.
The joint workshop between U.S. and Japanese researchers, supported by The U.
View Article and Find Full Text PDFAppl Clin Inform
January 2025
Division of Hospital Medicine, Department of Medicine, Hennepin Healthcare, Minneapolis, Minnesota, United States.
Objective: This study aimed to bridge the educational gap in clinical informatics (CI) at the residency level and stimulate interest in CI as a rewarding career path.
Methods: We developed an innovative CI and quality improvement (QI) resident rotation. This rotation replaced traditional QI blocks for Internal Medicine and several other residency programs, offering comprehensive exposure to core informatics and QI principles.
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