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Medial sural artery perforator flap following orbital exenteration.
BMJ Case Rep
November 2024
Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
An extended orbital exenteration defect in a male in his mid-80s was successfully reconstructed with a medial sural artery perforator flap. To our knowledge, this flap has not been described in the literature for such defects until now. While it may require meticulous intramuscular perforator dissection, it provides several advantages; it is thin, pliable, has a long pedicle of large calibre facilitating microanastomosis and provides adequate coverage where the amount of chimeric muscle can easily be tailored to the defect's surface area and volume.
View Article and Find Full Text PDFSimulating Upper Eyelid Ptosis During Neuromodulator Injections-An Exploratory Injection and Dissection Study.
J Cosmet Dermatol
December 2024
Department of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, Guangzhou, China.
Article Synopsis
- Aesthetic neuromodulator injections, commonly used to reduce upper facial wrinkles, can lead to a condition called blepharoptosis (drooping eyelids) in about 0.51% to 5.4% of cases.
- * The study analyzed injections in 18 supraorbital regions of nine human body donors to uncover how neuromodulators travel from outside to inside the orbit, impacting the levator palpebrae superioris muscle.
- * Findings revealed that a higher injection volume (0.5 cc) was linked to 19.44% of cases affecting eyelid elevation, suggesting that lower volumes and proper injection techniques could enhance safety during aesthetic treatments.*
Impact of ibrutinib on inflammation in a mouse model of Graves' orbitopathy.
Front Endocrinol (Lausanne)
September 2024
Department of Ophthalmology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Republic of Korea.
Article Synopsis
- The study explored the effects of ibrutinib, a BTK/ITK inhibitor, on inflammation in a mouse model of Graves' orbitopathy (GO), emphasizing its therapeutic potential.
- The research involved administering a recombinant plasmid to mice and measuring serum thyroid hormone levels and inflammatory markers, with a focus on histopathological changes in orbital tissues.
- Results showed that treatment with ibrutinib significantly reduced inflammatory markers and cytokine levels in the GO mice, indicating that BTK/ITK might play a key role in the inflammatory mechanisms of GO.
Anatomical considerations of medial eye wrinkles: Guidelines for botulinum neurotoxin injections.
J Cosmet Dermatol
November 2024
Asia-Pacific Aesthetic Academy, Hong Kong, Hong Kong.
Crow's feet lines in the lateral canthal region are a common concern among aging patients, initially appearing as dynamic wrinkles during facial expressions and becoming more pronounced with age. Botulinum neurotoxin temporarily paralyzes muscles by inhibiting acetylcholine release, smoothing wrinkles and enhancing skin's youthful appearance. Effective treatment requires tailored approaches considering individual anatomy and muscle activity.
View Article and Find Full Text PDFIntramuscular Hemangioma of Lateral Rectus Muscle with Rare Presentation as an Epibulbar Mass: A Case Report and Review of Literature.
Case Rep Oncol
July 2024
Department of Diagnostic and Molecular Pathology, University of Toronto, Toronto, ON, Canada.
Introduction: Intramuscular hemangiomas of extraocular muscles are extremely rare tumors that usually present as retro-orbital masses causing proptosis. We describe a previously unreported presentation, in the form of an epibulbar mass; this easily accessible location allows direct imaging, complete surgical resection, and histopathological confirmation, providing a unique perspective.
Case Presentation: A 69-year-old woman presented with a painless dark red mass in the lateral part of the right eye, which had been slowly enlarging over the last 18 months.
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