AI Article Synopsis
- The study examines the role of the Cilioretinal artery (CRA) in diabetic retinopathy (DR) and its impact on retinal thickness and diabetic macular edema (DME), focusing on the CRA's segmental supply influence.
- It analyzed 43 patients using fundus fluorescein angiography and optical coherence tomography to classify DME and assess CRA presence and location.
- Results showed CRA affects retinal thickness depending on its supply area, suggesting the need for more research to confirm these findings on a larger scale.
Article Abstract
Background: The supply of Cilioretinal artery (CRA) to different layers of the retina influences retinal pathologies such as diabetic retinopathy (DR). Since the supply of CRA is segmental, our aim was to analyze the location of CRA with respect to non - center involving diabetic macular edema (DME) differentiated by various segments and center involving DME based on Early Treatment of Diabetic Retinopathy Study (ETDRS) scale using optical coherence tomography (OCT).
Methods: A retrospective study was conducted in which forty-three patients with various stages of DR and the presence of CRA were identified. Presence and location of CRA was recognized using fundus fluorescein angiography. Classification of DME was based on ETDRS subfields on OCT.
Results: Evaluation of 26 men and 17 women with varying degrees of severity involving DR revealed the presence of unilateral CRA in 40 subjects and bilateral CRA in 3 subjects. When CRA supplied the central area, maximum retinal thickness was noted at the temporal quadrant (271.67 ± 164.02 μm) along with non - center involving DME (194.87 ± 121.06 μm); when CRA supplied the lower area, maximum retinal thickness was noted at the superior quadrant (293.64 ± 159.36 μm) along with center involving DME (395 ± 285.75 μm) and when it supplied the upper area, maximum retinal thickness was noted at the nasal quadrant (293.49 ± 176.18 μm) along with center involving DME (292 ± 192.79 μm).
Conclusion: The presence of CRA seems to influence the morphology of the retina amongst patients diagnosed with DR by altering the segments involved in DME based on its supply location. However, further studies with a larger sample size are warranted to strenghten this association.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818564 | PMC |
| http://dx.doi.org/10.1186/s12886-021-01812-x | DOI Listing |
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