Colostrum is the milk produced during the first few days after birth and contains high levels of immunoglobulins, antimicrobial peptides, and growth factors. Colostrum is important for supporting the growth, development, and immunologic defence of neonates. Colostrum is naturally packaged in a combination that helps prevent its destruction and maintain bioactivity until it reaches more distal gut regions and enables synergistic responses between protective and reparative agents present within it. Bovine colostrum been used for hundreds of years as a traditional or complementary therapy for a wide variety of ailments and in veterinary practice. Partly due to concerns about the side effects of standard Western medicines, there is interest in the use of natural-based products of which colostrum is a prime example. Numerous preclinical and clinical studies have demonstrated therapeutic benefits of bovine colostrum for a wide range of indications, including maintenance of wellbeing, treatment of medical conditions and for animal husbandry. Articles within this Special Issue of cover the effects and use bovine colostrum and in this introductory article, we describe the main constituents, quality control and an overview of the use of bovine colostrum in health and disease.
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http://dx.doi.org/10.3390/nu13010265 | DOI Listing |
J Dairy Sci
January 2025
Department of Agronomy, Food, Natural resources, Animals and Environment, University of Padova, Viale dell'Università 16, 35020 Legnaro (PD), Italy.
The quality of bovine colostrum, primarily determined by IgG concentration, is essential for the transfer of passive immunity and the development of the gastrointestinal tract in neonates. High IgG concentration in bovine colostrum (BC) is pivotal for the calf at first meal; however, while neonates often refuse to voluntarily drink the recommended amount of BC in the first hours of life, the dam frequently fails to produce a sufficient volume of colostrum at first milking. This study seeks to estimate the h of colostrum yield (CY) and its genetic correlations with total Ig, IgG, protein, and fat concentrations for the first time in the Italian Holstein population.
View Article and Find Full Text PDFNutrients
December 2024
Department of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Türkiye.
Bovine colostrum (BC), the first milk secreted by mammals after birth, is a trending alternative source for supplementing infants and children, offering benefits for gut and immune health. Its rich components, such as proteins, immunoglobulins, lactoferrin, and glycans, are used to fortify diets and support development. Preterm development is crucial, especially in the maturation of essential systems, and from 2010 to 2020, approximately 15% of all premature births occurred at less than 32 weeks of gestation worldwide.
View Article and Find Full Text PDFCan J Vet Res
January 2025
Key Laboratory of Feed Biotechnology, Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, No. 12 Zhong Guan Cun South Street, Haidian District, Beijing 100081, China (Han, Sun, Gu, J. Wang, X. Wang, Tao, Z. Wang, Liu); Jiangxi Agricultural University, No. 1225, Zhimin Avenue, Xinjian District, Nanchang City 330045, China (Gu).
Open Vet J
November 2024
Livestock and Wildlife Laboratory, Arid Lands Institute (I.R.A), University of Gabès, Médenine, Tunisia.
Background: Many protective proteins, including lactoferrin and heavy chain antibodies, are present in camel colostrum, giving it a distinctive composition. Beyond a broad spectrum of pathogens, these proteins demonstrate antibacterial properties.
Aim: The current research assessed the prophylactic properties of camel colostrum against F17.
Open Vet J
November 2024
Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Paratuberculosis is an infectious disease caused by subspecies (MAP). Typically, ruminant animals including cattle, buffalo, goats, and sheep are infected with MAP. Animals get infected with MAP in a number of ways, such as by eating or drinking contaminated food or water, or by nursing from an infected mother who may have contaminated teats or directly shed the organism in milk or colostrum.
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