Immune Responses Induced by mRNA Vaccination in Mice, Monkeys and Humans.

Vaccines (Basel)

Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, 161 64 Solna, Sweden.

Published: January 2021

In this concise review, we summarize the concepts behind mRNA vaccination. We discuss the innate and adaptive immune response generated by mRNA vaccines in different animal models and in humans. We give examples of viral infections where mRNA vaccines have shown to induce potent responses and we discuss in more detail the recent SARS-CoV-2 mRNA vaccine trials in humans.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831080PMC
http://dx.doi.org/10.3390/vaccines9010061DOI Listing

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