A Ru(ii)-BODIPY conjugate has been rationally designed and exhibits an intense absorption in the NIR region to boost lysosome-targeted PDT in vitro and in vivo. The advantages of Ru(ii) and BODIPY were successfully instilled into the conjugate to yield highly effective PDT efficacy against malignant melanoma A375 cells (PI = 3448) and A375 mice xenografts.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d0cc06926d | DOI Listing |
Publication Analysis
Top Keywords
ruii-bodipy conjugate
8
rational design
4
design lysosome-targeting
4
lysosome-targeting near-infrared
4
near-infrared absorbing
4
absorbing ruii-bodipy
4
conjugate photodynamic
4
photodynamic therapy
4
therapy ruii-bodipy
4
conjugate rationally
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!