Objective: To study the dynamics of thresholds of the electrically evoked compound action potential of the auditory nerve (ECAP) during neural responce telemetry (NRT) intraoperatively, at the time of activation of the cochlear implantation system (CI) and after 3 and 6 months.

Material And Methods: The study included 50 children aged 1 year to 4 years with bilateral sensorineural deafness, operated on by Nucleus CI512 Profile + CP900 CI systems («Cochlear», Australia). In all patients, the electrode array was fully inserted. The dynamics and thresholds of ECAP were recorded and assessed in dynamics: when performing NRT intraoperatively, when the CI system was activated, and after 3 and 6 months. To assess the thresholds, the 1st, 6th, 11th, 16th and 22nd electrodes of the multichannel electrode array were selected.

Results: The average threshold values and the NRT threshold profile determined intraoperatively and during measurements at different times after the activation of the CI system were significantly different (<0.001), while the average postoperative results were characterized by relative stability. It was shown that the thresholds determined on the electrodes located in the middle of the electrode lattice are more stable than the thresholds determined on the apical and basal electrodes. In most patients, the NRT threshold values determined at the time of the activation of the CI system and after 3 and 6 months were significantly lower than the thresholds determined intraoperatively. The data obtained allow us to conclude that NRT is a stable and accurate technique that allows you to objectify the process of setting up an individual card for the stimulation of the speech processor at the rehabilitation stage after cochlear implantation.

Download full-text PDF

Source
http://dx.doi.org/10.17116/otorino20208506117DOI Listing

Publication Analysis

Top Keywords

auditory nerve
8
electrically evoked
8
evoked compound
8
compound action
8
action potential
8
dynamics thresholds
8
nrt intraoperatively
8
electrode array
8
[threshold dynamics
4
dynamics auditory
4

Similar Publications

Background: Electrically evoked compound action potential (ECAP) can be used to measure the auditory nerve's response to electrical stimulation in cochlear implant (CI) users. In the Nurotron CI system, extracting the ECAP waveform from the stimulus artifact is time-consuming.

Method: We developed a new paradigm ("FastCAP") for use with Nurotron CI devices.

View Article and Find Full Text PDF

Vagus nerve stimulation rescues impaired fear extinction and social interaction in a rat model of autism spectrum disorder.

J Affect Disord

January 2025

Department of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX 75080, USA; Texas Biomedical Device Center (TxBDC), The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX 75080, USA. Electronic address:

Clinical diagnosis of anxiety disorders is highly prevalent in autism spectrum disorders (ASD). Available treatments for anxiety offer limited efficacy in the ASD population. Vagus nerve stimulation (VNS) has an anxiolytic effect in rats and, when coupled with fear extinction training, VNS enhances extinction of fear in healthy rats.

View Article and Find Full Text PDF

Background: The intraoperative measurements are essential steps in cochlear implant (CI) surgery for confirming correct electrode placement.

Objectives: To examine the intraoperative impedance and electrically evoked action potential (ECAP) measurement results of cochlear implant (CI) users with normal cochlear anatomy (NCA) and to compare them with CI users with inner ear malformations (IEM).

Material And Methods: This retrospective study included intraoperative data of 300 ears from 258 individuals using Medel and Cochlear (Nucleus) CI devices.

View Article and Find Full Text PDF

Neurobiological mechanism of music improving gait disorder in patients with Parkinson's disease: a mini review.

Front Neurol

January 2025

Department of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen, China.

Walking ability is essential for human survival and health. Its basic rhythm is mainly generated by the central pattern generator of the spinal cord. The rhythmic stimulation of music to the auditory center affects the cerebral cortex and other higher nerve centers, and acts on the central pattern generator.

View Article and Find Full Text PDF

Purpose: Cochlear implants (CI) are the most successful bioprosthesis in medicine probably due to the tonotopic anatomy of the auditory pathway and of course the brain plasticity. Correct placement of the CI arrays, respecting the inner ear anatomy are therefore important. The ideal trajectory to insert a cochlear implant array is defined by an entrance through the round window membrane and continues as long as possible parallel to the basal turn of the cochlea.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!