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Protective plant immune responses are elicited by bacterial outer membrane vesicles. | LitMetric

Protective plant immune responses are elicited by bacterial outer membrane vesicles.

Cell Rep

Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA; Department of Biochemistry, Duke University, Durham, NC 27710, USA. Electronic address:

Published: January 2021

Bacterial outer membrane vesicles (OMVs) perform a variety of functions in bacterial survival and virulence. In mammalian systems, OMVs activate immune responses and are exploited as vaccines. However, little work has focused on the interactions of OMVs with plant hosts. Here, we report that OMVs from Pseudomonas syringae and P. fluorescens activate plant immune responses that protect against bacterial and oomycete pathogens. OMV-mediated immunomodulatory activity from these species displayed different sensitivity to biochemical stressors, reflecting differences in OMV content. Importantly, OMV-mediated plant responses are distinct from those triggered by conserved bacterial epitopes or effector molecules alone. Our study shows that OMV-induced protective immune responses are independent of the T3SS and protein, but that OMV-mediated seedling growth inhibition largely depends on proteinaceous components. OMVs provide a unique opportunity to understand the interplay between virulence and host response strategies and add a new dimension to consider in host-microbe interactions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158063PMC
http://dx.doi.org/10.1016/j.celrep.2020.108645DOI Listing

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