Road safety strategies adopted worldwide have made significant progress in reducing road trauma, but have stagnated more recently. The situation in low- and middle-income countries is even worse with no significant decrease in fatality rates. Safety researchers have argued that adopting sociotechnical systems approach is necessary to make significant advancements and improvements. The aim of this study was to develop a control structure model of the Bangladesh road safety system by identifying the actors and organisations involved across the system. Expert stakeholders were identified and interviewed, and relevant information was gathered in order to generate the Systems Theoretic Accident Model and Process control structure model. Throughout the analysis of this model, differences in the control and feedback mechanisms of the system were identified, and road safety intervention recommendations were made. Future research should also predict potential risks within the system and propose proactive and preventative countermeasures. : In this article, a Systems Theoretic Accident Model and Process control structure model of the Bangladesh road safety system is developed, and the involved actors are identified. Based on interviews and workshops with expert stakeholders, differences in the controls and feedback mechanisms in the system were identified, and road safety intervention recommendations were made. BUET: Bangladesh University of Engineering and Technology.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/00140139.2021.1876928 | DOI Listing |
BMC Bioinformatics
January 2025
School of Computer Science and Technology, University of Science and Technology of China, 443 Huangshan Road, Hefei, 230027, China.
Background: Drug-drug interactions (DDIs) especially antagonistic ones present significant risks to patient safety, underscoring the urgent need for reliable prediction methods. Recently, substructure-based DDI prediction has garnered much attention due to the dominant influence of functional groups and substructures on drug properties. However, existing approaches face challenges regarding the insufficient interpretability of identified substructures and the isolation of chemical substructures.
View Article and Find Full Text PDFSurgeon
January 2025
Department of Arthritis, Affiliated Hospital of Shandong Second Medical University, 2428 Yuhe Road, Kuiwen District, Weifang City, Shandong Province, 261031, PR China. Electronic address:
Hallux valgus (HV) is the most common foot deformity. It has various pathogenic factors that make its pathogenesis challenging to understand. As the disease progresses, patients experience amplified pain and decreased activities, significantly affecting their quality of life.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma Xiang Road, Ma 'anshan, Anhui 243032, PR China. Electronic address:
Bacterial contamination is a very serious health and environmental problem, with the main source of toxicity being lipopolysaccharides in the cell walls of Gram-negative bacteria. Therefore, the development of effective analytical methods is crucial for the detection of lipopolysaccharide content. This work facilitates the efficient generation of precisely adjustable dual-mode signals for LPS detection in surface-enhanced Raman spectroscopy (SERS) and electrochemiluminescence (ECL) by inducing anisotropic morphological evolution of Au@Ag nanocubes (Au@AgNCs) through poly-cytosine (poly-C) DNA.
View Article and Find Full Text PDFAccid Anal Prev
January 2025
Western Australian Centre for Road Safety Research, School of Psychological Science, The University of Western Australia Perth Western Australia Australia.
Estimating reliable causal estimates of road safety interventions is challenging, with a number of these challenges addressable through analysis choices. At a minimum, developing reliable crash modification factors (CMFs) needs to address three critical confounding factors, i.e.
View Article and Find Full Text PDFInt J Neuropsychopharmacol
January 2025
Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai 201203, China.
Objective: This study aims to quantitatively evaluate the efficacy and safety of various treatment regimens for treatment-resistant depression (TRD) across oral, intravenous, and intranasal routes to inform clinical guidelines.
Methods: A systematic review identified randomized controlled trials on TRD, with efficacy measured by changes in the Montgomery-Åsberg Depression Rating Scale (MADRS). We developed pharmacodynamic and covariate models for different administration routes, using Monte Carlo simulations to estimate efficacy distribution.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!