Objectives: This study aims to assess the pullout strength of six different pedicle screw thread patterns.
Materials And Methods: A total of 36 sheep spines were divided into six groups including six spines in each group: fully threaded cortical (Type A), fully threaded spongeous (Type B), fully cortical threads in the proximal half and fully spongeous threads in the distal half (Type C), fully spongeous threads in the proximal half and fully cortical threads in the distal half (Type D), unthreaded proximal half with fully spongeous threads in the distal half (Type E), and unthreaded proximal half with fully cortical threads in the distal half (Type F). The axial compression-traction machine was used for biomechanical testing at a pullout rate of 1 mm/min.
Results: The mean values of pullout strength of the groups A, B, C, D, E, and F were 1112±7.52 N, 986±8.34 N, 646±3.88 N, 676±7.16 N, 609±9.52 N, and 769±6.49 N, respectively. There was a statistically significant difference between the screw groups A and B, C, D, E and F (p=0.036, p=0.028, p=0.04, p=0.039, and p=0.046, respectively). A statistically significant difference was observed between the groups B versus C and E (p=0.037 and p=0.021, respectively). There was no statistically significant difference between the groups B versus D and F (p=0.35 and p=0.61, respectively).
Conclusion: Fully threaded cortical pedicular screw design exhibited the strongest bone grasp compared to other thread designs. Further studies should be conducted in multidirectional force pattern on human spine to assess the six screw thread designs in a closer real-life setting simulation model.
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http://dx.doi.org/10.5606/ehc.2021.77004 | DOI Listing |
Microsurgery
January 2025
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Thinning of anterolateral thigh flap is challenging. Anatomical studies have shown variations in arterial branching patterns in the subcutaneous layer, which were suspected to be the reason for the high frequency of thinning failures. We attempted to visualize subcutaneous arterial courses preoperatively and perform thinning of perforator flaps using this information appropriately.
View Article and Find Full Text PDFJ Hand Surg Glob Online
November 2024
Department of Orthopaedics, The University of North Carolina School of Medicine, Chapel Hill, NC.
Purpose: Terminal extensor tenotomy or Dolphin tenotomy, is a described treatment for the management of distal interphalangeal (DIP) joint hyperextension in chronic boutonniere deformity. The purpose of this study was to investigate the effects of incremental partial Dolphin tenotomy in correcting boutonniere deformity, with a focus on evaluating the improvement in DIP joint hyperextension deformity and documenting the development of iatrogenic mallet finger.
Methods: Thirty-eight fingers from 10 cadaveric hands were used.
BMC Musculoskelet Disord
December 2024
Department of Orthopaedics and Traumatology Clinic, Başakşehir Çam ve Sakura City Hospital, İstanbul, Türkiye.
Background: This study aimed to assess important criteria, including osteoporosis, fracture type, implant position within the bone, fracture reduction, and radiographic union, in patients with intertrochanteric femoral fractures treated with proximal femoral nail (PFN) fixation and to show their effect on clinical outcomes.
Methods: PFN fixation was applied in 73 patients (41 females, 32 males; mean age: 64.5 ± 6.
Int J Mol Sci
December 2024
Renal Medicine, Kolling Institute of Medical Research, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Kidney fibrosis is the common pathological pathway in progressive chronic kidney disease (CKD), and current treatments are largely ineffective. The C-X-C chemokine receptor 4 (CXCR4) is crucial to fibrosis development. By using neural cell adhesion molecules as scaffolds with binding loops that mimic the shape of shark antibodies, fully humanized single-domain i-bodies have been developed.
View Article and Find Full Text PDFLancet Microbe
December 2024
Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA; Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA; Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USA. Electronic address:
Background: Egg-based inactivated quadrivalent seasonal influenza vaccine (eIIV4), cell culture-based inactivated quadrivalent seasonal influenza vaccine (ccIIV4), and recombinant haemagglutinin (HA)-based quadrivalent seasonal influenza vaccine (RIV4) have been licensed for use in the USA. In this study, we used antigen-specific serum proteomics analysis to assess how the molecular composition and qualities of the serological antibody repertoires differ after seasonal influenza immunisation by each of the three vaccines and how different vaccination platforms affect the HA binding affinity and breadth of the serum antibodies that comprise the polyclonal response.
Methods: In this comparative, prospective, observational cohort study, we included female US health-care personnel (mean age 47·6 years [SD 8]) who received a single dose of RIV4, eIIV4, or ccIIV4 during the 2018-19 influenza season at Baylor Scott & White Health (Temple, TX, USA).
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