Objective: The primary aim of this study was to investigate the contraceptive efficacy of a self-assembling uterine device (iUPOD™) in the mare. In addition, the effects of iUPODs on oestrous cyclicity, uterine health and circulating concentrations of cortisol were evaluated.
Methods: Domestic mares underwent oestrous monitoring and artificial insemination. After subsequent ovulation, mares underwent either placement (n = 7) or sham placement (n = 7; controls) of an iUPOD device. Devices were left in place for at least 3 months. Pregnancy diagnoses were carried out 14 days post-ovulation, with any pregnancies terminated at 28 days post-ovulation. All mares underwent weekly blood sampling with or without reproductive examinations throughout the study. Towards the end of the study, multiple serum samples collected over three consecutive days were analysed for concentrations of cortisol. Endometrial biopsies were collected before artificial insemination and during the subsequent breeding season. Endometrial cytology and bacterial cultures were performed before device removal (iUPOD mares) or at the end of the study (control mares).
Results: Pregnancies were diagnosed in 0 of 7 iUPOD mares versus 7 of 7 control mares. Placement of iUPODs was associated with extended luteal phases and variable accumulations of intra-uterine fluid. Bacterial culture results suggested that the mild endometritis associated with iUPODs was sterile in six of seven mares. Short-term placement of iUPODs had no detrimental effects on endometrial architecture. Mean serum cortisol concentrations were significantly lower in iUPOD mares than control mares.
Conclusion: iUPODs represent a promising means of fertility control in the mare.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/avj.13055 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
De Quervain's disease: Ultrasound-guided release.
Hand Surg Rehabil
January 2025
Orthopedic Surgery Department, CHU Caremeauux,Debré, Nîmes, France.
Purpose: This study aimed to evaluate the outcomes of a novel antegrade, ultrasound-guided release of the first extensor tendon compartment for treating De Quervain's disease.
Methods: We conducted a retrospective, single-center study of 34 patients who underwent ultrasound-guided release of the first extensor compartment for clinically diagnosed De Quervain's disease between June 2022 and December 2023. Inclusion criteria included age >18 years and failure of conservative treatment (e.
Ultrasound-guided trigger thumb release.
Hand Surg Rehabil
January 2025
Orthopedic Surgery Department, CHU Caremeaux, Nîmes, France.
The purpose of this study was to evaluate the results of a novel retrograde ultrasound-guided A1 pulley release technique for the treatment of trigger thumb. We conducted a retrospective, single-center study of 42 patients who underwent ultrasound-guided A1 pulley release for clinically diagnosed trigger thumb between September 2022 and December 2023. All cases were graded according to the Green classification of trigger finger severity.
View Article and Find Full Text PDFSecondary intact capsulectomy with seroma without implant: revision of an incomplete treatment of BIA-ALCL - a case report.
Case Reports Plast Surg Hand Surg
January 2025
Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Sant' Andrea Hospital, Rome, Italy.
Background: Breast Implant Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) is a haematological malignancy which may occur in patients with textured breast implant history. While typically diagnosed at an early stage with good prognosis, it may present with local residual disease due to incomplete surgical excision.
Case Presentation: We describe the case of a 42 year-old woman with a history of bilateral breast augmentation for cosmetic purposes 21 years prior, who developed recurring seroma of the left side.
Essential oil supplementation improves insulin sensitivity and modulates the plasma metabolome of hyperinsulinemic horses.
Front Vet Sci
December 2024
Department of Animal and Food Sciences, University of Kentucky, Lexington, KY, United States.
The objective of this study was to investigate the effect of essential oil (EO) supplementation on insulin sensitivity (IS) and the plasma metabolome in insulin dysregulated (ID) horses. Horses were blocked by degree of IS and assigned randomly to treatment: oral daily bolus (50 mL) of either a plant derived EO supplement or carrier (CON). Mares were housed in dry lots with access to grass hay and supplemented individually twice daily with a concentrate to meet nutrient requirements for mature horses.
View Article and Find Full Text PDFLeptospiral infection in domestic mares in North Queensland.
Aust Vet J
November 2024
Discipline of Veterinary Science, College of Public Health, Medical and Veterinary Sciences, James Cook University, Douglas, Queensland, Australia.
Article Synopsis
- Leptospira species are globally distributed, predominantly in tropical areas, and can infect various animals; they are primarily spread through urine, though some species, like horses, may also harbor the bacteria in their reproductive tract.
- A study was conducted on 50 healthy non-breeding mares to investigate leptospiral infection via serum and endometrial swabs, in addition to urine samples where available.
- The study revealed a 48% seroprevalence of leptospirosis with the most common serovars being Arborea, Bratislava, and Australis, while PCR testing found low positivity in endometrial and urine samples, marking the first identification of serovar Bratislava in Australian horses.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!