We present a neural optimization model trained with reinforcement learning to solve the coordinate ordering problem for sets of star glyphs. Given a set of star glyphs associated to multiple class labels, we propose to use shape context descriptors to measure the perceptual distance between pairs of glyphs, and use the derived silhouette coefficient to measure the perception of class separability within the entire set. To find the optimal coordinate order for the given set, we train a neural network using reinforcement learning to reward orderings with high silhouette coefficients. The network consists of an encoder and a decoder with an attention mechanism. The encoder employs a recurrent neural network (RNN) to encode input shape and class information, while the decoder together with the attention mechanism employs another RNN to output a sequence with the new coordinate order. In addition, we introduce a neural network to efficiently estimate the similarity between shape context descriptors, which allows to speed up the computation of silhouette coefficients and thus the training of the axis ordering network. Two user studies demonstrate that the orders provided by our method are preferred by users for perceiving class separation. We tested our model on different settings to show its robustness and generalization abilities and demonstrate that it allows to order input sets with unseen data size, data dimension, or number of classes. We also demonstrate that our model can be adapted to coordinate ordering of other types of plots such as RadViz by replacing the proposed shape-aware silhouette coefficient with the corresponding quality metric to guide network training.
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http://dx.doi.org/10.1109/TVCG.2021.3052167 | DOI Listing |
JMIR Form Res
March 2025
Program in Digital Medicine, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, United States.
Background: Screening for cognitive impairment in primary care is important, yet primary care physicians (PCPs) report conducting routine cognitive assessments for less than half of patients older than 60 years of age. Linus Health's Core Cognitive Evaluation (CCE), a tablet-based digital cognitive assessment, has been used for the detection of cognitive impairment, but its application in primary care is not yet studied.
Objective: This study aimed to explore the integration of CCE implementation in a primary care setting.
Chem Soc Rev
March 2025
Department of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Whilst bis(trimethylsilyl)amide has been used extensively as a ligand across the periodic table, the chemistry of its heavier group 15 congeners is relatively underdeveloped. However, bis(trimethylsilyl)phosphide coordination chemistry has provided unique structural motifs and has also shown potential applications in catalysis, materials science, and bioinorganic chemistry. This review, which marks 55 years since the first report of a bis(trimethylsilyl)phosphide complex, provides a comprehensive overview of the synthesis, characterisation and reactivity of structurally authenticated s-, p-, d- and f-block metal complexes of this ligand, focusing on salient single crystal XRD and NMR spectroscopic data.
View Article and Find Full Text PDFNat Commun
March 2025
Department of Orthopaedics, Shanghai Key Laboratory of Orthopaedic Implant, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
The proper assembly and maturation of collagens necessitate the orchestrated hydroxylation and glycosylation of multiple lysyl residues in procollagen chains. Dysfunctions in this multistep modification process can lead to severe collagen-associated diseases. To elucidate the coordination of lysyl processing activities, we determine the cryo-EM structures of the enzyme complex formed by LH3/PLOD3 and GLT25D1/ColGalT1, designated as the KOGG complex.
View Article and Find Full Text PDFOsong Public Health Res Perspect
March 2025
Division of International Affairs, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Z Orthop Unfall
March 2025
Klinik und Poliklinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinikum Leipzig, Leipzig, Germany.
With the new licensing regulations and the National Competence-Based Learning Objectives Catalogue for Medicine (NKLM), the learning objectives and certificates of achievement are no longer assigned to specific subjects. In addition to the opportunity for the subject of orthopaedics and trauma surgery to present itself more prominently and at an earlier stage, there is also a need to identify the relevant subject-related learning objectives in order to integrate them into the curricula and prepare for internal faculty discussions on teaching assignments. At present, it remains unclear whether the new licensing regulations will be accompanied by the initially planned complete restructuring in the form of the so-called Z-curriculum, but the new learning objectives of the NKLM will become part of the training for future doctors.
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