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Rare Prekallikrein Deficiency Identified During Workup of Isolated Prolonged Activated Partial Thromboplastin Time.
Ochsner J
January 2024
Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Irvine, CA.
Prolongation of the activated partial thromboplastin time (aPTT) may signify an intrinsic factor deficiency or the presence of an inhibitor of coagulation, potentially placing a patient at increased risk for bleeding. However, a contact factor (ie, factor XII, prekallikrein, and high molecular weight kininogen) deficiency, which may also cause a prolonged aPTT, is not associated with clinical bleeding. A 71-year-old female had an isolated prolonged aPTT discovered during preoperative laboratory testing.
View Article and Find Full Text PDFPrevalence of anxiety and depression in former elite athletes: a systematic review and meta-analysis.
BMJ Open Sport Exerc Med
December 2024
School of Health & Sport Sciences, Liverpool Hope University, Liverpool, UK.
Objectives: To summarise the evidence regarding the prevalence of anxiety and depression in former elite athletes compared with the general population.
Design: Systematic review and meta-analysis.CRD42022347359.
Types of cell death in diabetic cardiomyopathy: insights from animal models.
Acta Biochim Biophys Sin (Shanghai)
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Department of Anesthesiology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Approximately one-tenth of the global population is affected by diabetes mellitus, and its incidence continues to rise each year. In China, 1.4 million patients die from diabetes-related complications every year.
View Article and Find Full Text PDFLong-Term Outcomes of Adolescent Outpatient Treatment for Substance Use Problems: Exploring the Co-occurrence of Mental Health and Substance Use Problems.
Scand J Child Adolesc Psychiatr Psychol
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Department of Pedagogy and Learning, Linnaeus University, Växjö, Sweden.
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