Hydrosulphite (HSO ), as a common and important chemical reagent, is widely used in everyday life, however excessive use and abuse of HSO can cause potential harmful effects on the environment and in biological health. In this paper, we describe the design and preparation of a colorimetric and ratiometric fluorescence probe for the visual detection of HSO (excitation wavelengths were, respectively, 336 nm and 520 nm). This method showed some advantages including simple preparation, high selectivity, fast response, and significant colour and fluorescence ratio (F /F ) changes in the presence of HSO . In addition, this probe was used successfully for the detection of HSO in real water samples and showed a good recovery rate range.
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Article Synopsis
- * A newly designed FUCL probe, PT-1, shows high sensitivity and selectivity in detecting HSO, with a detection limit significantly lower than traditional methods (43 nM vs. 93 nM).
- * PT-1 not only targets mitochondria for real-time monitoring of HSO in living cells but also successfully tracks HSO levels in mice experiencing drug-induced liver injury using FUCL imaging.
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