Background And Purpose: Current commercial surface scanning systems are not able to monitor patients during radiotherapy fractions in closed-bore linacs during adaptive workflows. In this work a surface scanning system for monitoring in an O-ring linac is proposed.
Methods And Materials: A depth camera was mounted at the backend of the bore. The acquired surface point cloud was transformed to the linac coordinate system after a cube detection calibration step. The real-time surface was registered using an Iterative Closest Point algorithm to a reference region-of-interest of the body contour from the planning CT and of a depth camera surface acquisition from the first fraction. The positioning accuracy was investigated using anthropomorphic 3D-printed phantoms with embedded markers: a head, hand and breast. To simulate clinically observed positioning errors, each phantom was placed 24 times with 0-10 mm and 0-8° offsets from the planned position. At every position a cone-beam CT (CBCT) was acquired and a surface registration performed. The surface registration error was determined as the difference between the surface registration and the CBCT-to-CT fiducial marker registration.
Results: The registration errors were (mean ± SD): lat: 0.4 ± 0.8 mm, vert: -0.2 ± 0.2 mm, long: 0.3 ± 0.5 mm and Yaw: -0.2 ± 0.6°, Pitch: 0.4 ± 0.2°, Roll: 0.5 ± 0.8° for the body contour reference, and lat: -0.7 ± 0.7 mm, vert: 0.3 ± 0.2 mm, long: 0.2 ± 0.5 mm and Yaw: -0.5 ± 0.5°, Pitch: 0.1 ± 0.3°, Roll: -0.7 ± 0.7° for the captured surface reference.
Conclusion: The proposed single camera intra-bore surface system was capable of accurately detecting phantom displacements and allows intrafraction motion monitoring for surface guided radiotherapy inside the bore of O-ring gantries.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807582 | PMC |
http://dx.doi.org/10.1016/j.phro.2019.07.003 | DOI Listing |
Front Biosci (Landmark Ed)
January 2025
Department of Food Biotechnology and Microbiology, Institute of Food Sciences, Warsaw University of Life Sciences - SGGW, 02-776 Warsaw, Poland.
Background: This study investigated the selenium-binding capacity of the biomass of two yeast strains, American Type Culture Collection (ATCC) 7090 and CCY 20-2-26.
Methods: The studies carried out methods of bioaccumulation by yeast biomass. Inorganic selenium was added to the culture media as an aqueous solution of NaSeO at concentrations ranging from 0 to 40 mg Se/L.
J Integr Neurosci
January 2025
Neuroscience Department, University of Connecticut Health, School of Medicine, Institute for Systems Genomics, Farmington, CT 06030, USA.
Background: In neuroscience, Ca imaging is a prevalent technique used to infer neuronal electrical activity, often relying on optical signals recorded at low sampling rates (3 to 30 Hz) across multiple neurons simultaneously. This study investigated whether increasing the sampling rate preserves critical information that may be missed at slower acquisition speeds.
Methods: Primary neuronal cultures were prepared from the cortex of newborn pups.
Luminescence
January 2025
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
The environmental impact of chemicals used in aquaculture, particularly nitrofurantoin, has raised global concern. Nitrofurantoin, a broad-spectrum antimicrobial, is commonly used in aquaculture despite safety risks. Determination of nitrofurantoin in water samples of fish ponds is necessary to ensure the safety and quality of seafood.
View Article and Find Full Text PDFJ Oral Rehabil
January 2025
Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.
Background: Surface electromyography (sEMG) has been used in a wide range of studies conducted in the field of dysphagia.
Objectives: The main aim of this case-control study is to obtain how submental and infrahyoid sEMG signals differ based on residue, penetration and aspiration.
Methods: A total of 100 participants (50 patients with suspected dysphagia and 50 healthy controls) were enrolled in the present study.
J Sep Sci
January 2025
Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic compounds resulting from incomplete burning of organic materials. This work describes the successful layer-by-layer fabrication of a novel zinc oxide nanocomposite made of zinc oxide nanoparticles, aniline, sodium dodecyl sulfate, and modified multi-walled carbon nanotubes on a stainless steel wire by electrodeposition. The coating and extraction conditions were screened, optimized, and validated using factorial design and central composite design, respectively.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!