Unlabelled: The coexistence of two immune-mediated diseases in the same patient is unusual. Takayasu's arteritis (TA), which is a chronic granulomatous vasculitis, was discovered in a 47-year-old woman followed for tubulointerstitial nephritis and uveitis syndrome (TINU syndrome). We present the first case of this association.
Learning Points: Rare autoimmune diseases can coexist in the same patient.Physical examination is important so that coexisting diseases can be identified.Takayasu's arteritis was discovered as an incidental finding in a patient followed fortubulointerstitial nephritis and uveitis syndrome.
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http://dx.doi.org/10.12890/2020_002040 | DOI Listing |
J Am Soc Nephrol
January 2025
Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.
The renal tubule and collecting duct express a large number of proteins, all having putative immunoreactive motives. Therefore, all can be the target of pathogenic autoantibodies. However, autoimmune tubulopathies seem to be rare and we hypothesize that they are underdiagnosed.
View Article and Find Full Text PDFJ Comp Pathol
December 2024
Departamento de Ciências Veterinárias, Universidade Federal do Paraná, Setor Palotina, Rua Pioneiro, 2153, Palotina, Paraná, 85950-000, Brazil.
Protothecosis is an infectious disease caused by unicellular algae of the genus Prototheca, which are mainly known for causing mastitis in farm animals. However, there are reports of protothecosis in humans and other animals, such as dogs and cats, which develop cutaneous lesions or systemic lesions. Dogs with the systemic form generally develop bloody diarrhoea and blindness and neurological signs may also occur.
View Article and Find Full Text PDFSarcoidosis is a multisystem granulomatous disorder of undetermined etiology that usually affects the lungs. It is a rare presentation to have an association between sarcoidosis and pancreatitis. We present a challenging case of acute pancreatitis and kidney dysfunction which had been diagnosed later to be sarcoidosis.
View Article and Find Full Text PDFBMC Nephrol
September 2024
Department of Pathology, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Ocul Immunol Inflamm
September 2024
Connecticut Uveitis Foundation, West Hartford, Connecticut, USA.
Purpose: To report two patients who presented with scleritis associated with tubulointerstitial nephritis and uveitis syndrome (TINU).
Results: A 13-year-old male initially presenting with unilateral panuveitis with scleritis in the fellow eye was ultimately diagnosed with TINU. A 33-year-old male previously diagnosed with TINU presented with recurrent bilateral episcleritis as well as bilateral scleritis eight years after his first episode of bilateral anterior uveitis.
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