Respiratory gas-exchange data from progressive exercise tests are typically interpreted by visual inspection. Attempts to objectify such interpretation have applied particular parametric models which limit the measures which can be studied and the inferences which can be made. We use a known spline-smoothing procedure which fits a continuous curve to such data, yielding confidence intervals for the curve and for its first and second derivatives. Rules can be made which use the derivatives to infer features of a curve's shape and to relate features from different curves in the same data set. In this way complex interpretations can be made objective, so that they may be adequately tested.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/0010-4809(88)90038-9 | DOI Listing |
BMC Pediatr
March 2025
Department of Pediatrics, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China.
Objective: This study aimed to investigate the relationship between body mass index (BMI) during adolescence and the future risk of developing hypertension, with a particular focus on potential sex differences.
Methods: This study was a secondary analysis based on a cohort study involving 2,020 adolescents aged 10-15 years who underwent health check-ups at the MJ Health Screening Center between 1999 and 2008. Cox proportional hazards regression models were used to evaluate the association between BMI and hypertension risk, with stratification by gender.
3D Print Med
March 2025
Division of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Background: Computer-assisted surgery has transformed the approach to jaw resection and reconstruction in recent years. However, the extensive time and technical expertise needed for the planning and creation of patient-specific implants and guides have posed significant challenges for many surgeons in the field. This study introduces a novel algorithm designed to streamline the traditionally intricate and time-consuming Computer-Aided Design (CAD) process for developing patient-specific implants (PSIs).
View Article and Find Full Text PDFBMC Endocr Disord
March 2025
The First Hospital of Jilin University, 1 Xinmin Street, Changchun, Jilin, 130021, China.
Background: Estimated small dense low-density lipoprotein cholesterol (sdLDL-C) was related to atherosclerosis, coronary heart disease and metabolic syndrome. Despite these findings, limited evidence is available on the relationship between sdLDL-C levels and the onset of diabetes mellitus (DM).
Methods: The study analyzed data from 118,080 adults enrolled at the Rich Healthcare Group between 2010 and 2016.
BMC Infect Dis
March 2025
Department of Blood Transfusion, Xiangya Hospital, Central South University, Changsha, China.
Background: In recent years, the hemoglobin, albumin, lymphocyte, and platelet (HALP) score has emerged as a potential marker of immunological and nutritional status. This study aimed to evaluate the association between the HALP score and prognosis in patients with sepsis.
Methods: This retrospective cohort study analyzed sepsis patients using clinical data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database.
Sci Rep
March 2025
School of Information Science and Engineering, Northeastern University, Shenyang, 110819, China.
The paper proposes a new M2ACD(Multi-Actor-Critic Deep Deterministic Policy Gradient) algorithm to apply trajectory planning of the robotic manipulator in complex environments. First, the paper presents a general inverse kinematics algorithm that transforms the inverse kinematics problem into a general Newton-MP iterative method. The M2ACD algorithm based on multiple actors and critics is structured.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!