EVALUATION OF THE TREATMENT EFFECTIVENESS OF GINGIVITIS BY THE ORAL DYSBIOSIS INDEX IN PATIENTS WITH DIFFERENT REACTIONS OF PSYCHOPHYSIOLOGICAL MALADAPTATION.

Objective: The aim: The purpose of this study was to evaluate the dynamics of changes of oral cavity dysbiosis index in patients with various reactions of psychophysiological maladaptation after treatment of gingivitis in different observation terms.

Patients And Methods: Materials and methods: Study was conducted on the basis of Department of Therapeutic Dentistry of Ternopil National Medical University during 1 year from January 2018 till January 2019. The study involved treatment of 58 patients 19-44-years old with gingivitis on a background of different psycho-physiological maladaptation reactions, of whom was formed the I main group (37 people) and the II control group (21 people). For evaluation of the effectiveness of the proposed treatment and prevention complexes, we determined the dynamics of changes of oral cavity dysbiosis index after the treatment of gingivitis at different study times.

Results: Results: In patients with gingivitis lysozyme activity increased by 15.02% (p <0.01) and urease activity decreased by 24.46% (p <0.05), according to before-treatment data. In patients of the first group, the oral dysbiosis index decreased in 1.5 times fold with respect to before-treatment data (0.37 ± 0.09 vs. 0.56 ± 0.08, p> 0.05).

Conclusion: Conclusions: Therefore, as a result of the use of proposed treatment and prevention complex was able to increase the activity of lysozyme and reduce urease activity, which generally improved the oral cavity dysbiosis in the main group, which after 1 year of observation was equal to the medium degree in patients with all types of psychophysiological reactions.