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http://dx.doi.org/10.1111/bjd.19814DOI Listing

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Article Synopsis
  • Agmination and satellitosis in pigmented blue lesions are poorly understood phenomena that can appear in various skin conditions, including benign and malignant lesions like blue nevi and melanoma.
  • Non-invasive imaging technologies, such as dermoscopy, reflectance confocal microscopy (RCM), and dynamic Optical coherence tomography (D-OCT), can assist in diagnosing skin cancers but have limitations in studying these lesions.
  • The paper presents four new cases of agminated pigmented lesions and emphasizes the need for more literature and clinical-pathological correlations to improve diagnostic confidence among clinicians.
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Spitz naevus (SN) are benign melanocytic lesions, which are classified into solitary, agminated, or disseminated forms. The most common form is solitary SN, typically occurring on the face and extremities of children. However, the disseminated SN is a rare presentation that can be either rapid eruptive or non-eruptive.

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Background: The conventionally understood pathogenesis of agminated Spitz nevi includes a mosaic HRAS mutation followed by copy number gains in 11p. However, we have recently observed agminated presentations of fusion-driven melanocytic neoplasms.

Methods: We retrieved cases from our database of benign fusion-induced melanocytic neoplasms with an agminated presentation.

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Agminated Halo Nevus: A Novel Presentation.

Am J Dermatopathol

June 2023

Department of Dermatology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Halo nevus is a benign type of melanocytic nevi commonly found in children and manifests as a central pigmented part surrounded by a well-defined hypopigmented area. Halo nevi are commonly located on the trunk. The central nevus may show partial or complete regression, whereas the associated halo may persist or enlarge.

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