Tumours growing in the sella turcica are mostly pituitary adenomas. We describe a rare case of primary intrasellar schwannoma with intratumoral bleeding. A 38-year-old man presented with headache in association with bilateral supratemporal quadrantopsia. MRI showed an intrasellar mixed signal mass lesion with suprasellar extension. The majority of the pituitary hormones were normal. He was diagnosed as non-functional pituitary adenoma with pituitary apoplexy. Subtotal resection was achieved eventually via an endoscopic transnasal trans-sphenoidal approach. The histopathologic diagnosis was schwannoma. It is the first intrasellar schwannoma with intratumoral hemorrhage in literature to date. It implied that the primary intrasellar schwannoma has potential risk of intratumoral bleeding, which should be considered in the differential diagnoses of sellar lesions.
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http://dx.doi.org/10.1016/j.neuchi.2020.12.003 | DOI Listing |
Surg Neurol Int
September 2022
Department of Neurosurgery, University of Cincinnati, Cincinnati, United States.
Background: Schwannomas are cranial and spinal nerves' sheath tumors accounting for up to 8% of all intracranial neoplasms. Although typical intracranial schwannomas originate from Schwann cells surrounding cranial nerves, ectopic schwannomas are not associated with a known cranial nerve or have an unknown origin. The location of schwannomas may impose clinical challenges.
View Article and Find Full Text PDFNeurochirurgie
September 2021
Neurosurgical department, Second Affiliated Hospital, Xi'an Jiaotong University, 710004 Xi'an, China.
Tumours growing in the sella turcica are mostly pituitary adenomas. We describe a rare case of primary intrasellar schwannoma with intratumoral bleeding. A 38-year-old man presented with headache in association with bilateral supratemporal quadrantopsia.
View Article and Find Full Text PDFWorld Neurosurg
December 2016
Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China; Brain Science Research Institute, Shandong University, Jinan, Shandong Province, People's Republic of China. Electronic address:
Background: Intracranial schwannomas usually arise from sensory nerves with a predilection for the trigeminal nerve and the vestibular component of the eighth cranial nerve (VIII). Schwannoma arising in the sella and extending into the suprasellar region is exceedingly rare and easily misdiagnosed as pituitary macroadenoma. Only 26 cases of intrasellar schwannomas have been reported in the literature.
View Article and Find Full Text PDFOncol Lett
March 2016
Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China.
Intrasellar schwannoma is extremely rare, and only a few cases have been reported in the literature to date. In the present study, the clinical, radiological and pathological features of a 50-year-old male patient with primary intrasellar schwannoma are presented. The patient presented with decreased visual acuity, and a subsequent computed tomography (CT) scan revealed a giant well-demarcated intrasellar mass with suprasellar extension, without cavernous sinus invasion.
View Article and Find Full Text PDFMedicine (Baltimore)
March 2016
From the Department of Neurosurgery (XK, WM, YL, YY, BX, JW, YY, JG, WL, ZX, WD, ZR, CS, RW); Department of Pathology (HW), Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
In central nervous system, schwannomas, as ubiquitous tumors, mostly originate from sensory nerves like auditory and trigeminal nerves. However, intrasellar schwannomas are extremely rare. They are often misdiagnosed as pituitary adenomas.
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