Isoflurane and primary pulmonary hypertension.

Anaesthesia

Department of Anaesthesia, Mount Sinai Hospital, University of Toronto, Ontario, Canada.

Published: January 1988

Primary pulmonary hypertension is a rare and fatal disease. These patients represent an anaesthetic challenge because of the high mortality associated with the marked intra-operative increase in pulmonary vascular resistance and right ventricular decompensation. This is a first case report which demonstrates the safe and beneficial effects of isoflurane in lowering pulmonary arterial pressure and pulmonary vascular resistance in such a patient for a short surgical procedure. The anaesthetic considerations in these patients are discussed.

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http://dx.doi.org/10.1111/j.1365-2044.1988.tb05417.xDOI Listing

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