Interamerican Society of Cardiology (IASC) position statement: Chlorthalidone vs. thiazide- diuretics.

Int J Cardiol Hypertens

Medical Affairs, Ipca Laboratories Limited, Mumbai, India.

Published: December 2020

The Interamerican Society of Cardiology (IASC) Position Statement for hypertension management in Latin America is a practical and useful review of five different hypertension guidelines. Though, thiazide diuretics have been recommended as firstline option, the position statement needs to highlight differences the thiazide class. Chlorthalidone is structurally and pharmacokinetically distinct from thiazide- iuretics like hydrochlorothiazide with a longer half-life and 24-h anti-hypertensive effect. It has been shown to reduce cardiovascular morbidity and mortality in several landmark studies evaluating anti-hypertensives.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803026PMC
http://dx.doi.org/10.1016/j.ijchy.2020.100054DOI Listing

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