Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension.

Int J Cardiol Hypertens

Department of Cardiology, The 1st Affiliated Hospital of Dalian Medical University, Lianhe Road, No. 193, Shahekou District, Dalian, Liaoning, China.

Published: August 2019

Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LA and LA) were lower in group II compared with group I ( ​< ​0.05). Multivariate regression analysis showed that LA was independently related to PAC (β ​= ​-0.581,  ​< ​0.001). In conclusion, PAC is associated with LA conduit function in hypertension.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803024PMC
http://dx.doi.org/10.1016/j.ijchy.2019.100015DOI Listing

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