Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a significant burden on healthcare. Acute sinusitis can be one of its deadliest presentations as it can quickly lead to orbitocranial extension with complications including blindness, brain abscess and death. Previously believed to affect immunocompromised individuals only, community-associated MRSA is now known to affect healthy individuals too. The seriousness of MRSA infection increases manifold when the infection occurs in pregnant women who are immune modulated. We present a case of a 34-year-old pregnant lady who presented with a severe headache for two days. She had acute sinusitis that involved right orbit in less than 24 hours. She was promptly managed with intravenous antibiotics and drainage of abscess that revealed MRSA. Fortunately, the patient made a complete recovery. The purpose of this case report is to emphasize on keeping a high index of suspicion of MRSA for all soft tissue infections. Early recognition, proper evaluation and timely and appropriate treatment can prove lifesaving.
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http://dx.doi.org/10.7759/cureus.12054 | DOI Listing |
Vestn Otorinolaringol
December 2024
Morozovskaya Children's City Clinical Hospital, Moscow, Russia.
Introduction: The differential diagnosis of orbital complications of rhinosinusitis with diseases of the lacrimal sac in childhood remains unresolved both due to the similarity of the symptoms of the diseases and due to certain diagnostic difficulties requiring computed tomography.
Objective: To develop an algorithm for routing a patient to the emergency department of a multidisciplinary emergency hospital based on clinical and diagnostic distinctive features of sinusitis with orbital complications and diseases of the lacrimal sac with reactive edema of the eyelids.
Materials And Methods: A retrospective cohort analysis of children's medical histories, who were treated in the otorhinolaryngological and ophthalmological departments of the Morozovskaya Children's City Clinical Hospital during 2022 was performed for orbital complications of rhinosinusitis or dacryocystitis with reactive edema of the eyelids.
Infect Control Hosp Epidemiol
December 2024
Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.
International Classification of Diseases, Tenth Revision (ICD-10) billing data used in outpatient stewardship metrics is under-described for acute and chronic sinusitis. We found that different sinusitis ICD-10 definitions impacted antibiotic prescribing rates (APRs). Chronic sinusitis ICD-10s dilute overall sinusitis APR, particularly in primary care settings and should be examined separately.
View Article and Find Full Text PDFJ Pediatric Infect Dis Soc
December 2024
University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, CSC Room H4 554, Madison, WI.
medRxiv
December 2024
School of Public Health, University of California, Berkeley, Berkeley, California, United States.
Background: (pneumococcus) causes invasive pneumococcal disease (IPD) and non-invasive acute respiratory infections (ARIs). Three pneumococcal conjugate vaccines (PCVs) are recommended in the United States with additional products in clinical trials. We aimed to estimate 1) proportions of IPD cases and pneumococcal ARIs caused by serotypes targeted by existing and pipeline PCVs and 2) annual U.
View Article and Find Full Text PDFBMC Prim Care
December 2024
Department of Endocrinology, University hospital Dubrava, Zagreb, Croatia, and School of Medicine, and University of Zagreb, Zagreb, Croatia.
Background: Acute respiratory tract infections are common in primary healthcare care settings and frequently result in antibiotic prescriptions, despite being primarily viral. There is scarcity of research examining impact of academic detailing (AD) intervention on prescribing practices for these infections in resource-constrained healthcare settings like southeastern Europe. Therefore aim of this study was to evaluate impact of AD intervention as an antimicrobial stewardship measure on antibiotic prescribing for acute respiratory tract infections in primary setting in Croatia which is located in southeastern Europe.
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