AI Article Synopsis
- The study aimed to identify factors that determine the severity of isolated secondary tricuspid regurgitation in patients with normal left ventricular function.
- Researchers analyzed 100 patients, discovering that right atrial volume and tethering area significantly affect tricuspid regurgitation severity, with specific measurements indicating higher risk.
- The findings suggest that severe tricuspid regurgitation is linked to dilated right atrium and leaflet tethering, while right ventricular size changes progressively with increasing severity.
Article Abstract
Background: A better understanding of the mechanism of tricuspid regurgitation severity would help to improve the management of this disease.
Aim: We sought to characterize the determinants of isolated secondary tricuspid regurgitation severity in patients with preserved left ventricular ejection fraction.
Methods: This was a prospective observational multicentre study. Patients with severe tricuspid regurgitation were asked to participate in a registry that required a control echocardiogram after optimization of medical treatment and a follow-up. Patients had to have at least mild secondary tricuspid regurgitation when clinically stable, and were classified according to five grades of tricuspid regurgitation severity, based on effective regurgitant orifice area.
Results: One hundred patients with tricuspid regurgitation (12 mild, 31 moderate, 18 severe, 17 massive and 22 torrential) were enrolled. Right atrial indexed volume and tethering area were statistically associated with the degree of tricuspid regurgitation (P<0.001 and P=0.005, respectively). When the tricuspid annular diameter was≥50mm, the probability of having severe tricuspid regurgitation or a higher grade was>70%. For an increase of 10mL/m in right atrial volume, the effective regurgitant orifice area increased by 4.2mm, and for an increase of 0.1cm in the tethering area, the effective regurgitant orifice area increased by 2.35mm. The degree of right ventricular dilation and changes in tricuspid morphology were significantly related to tricuspid regurgitation severity class (P<0.001). No significant difference in right ventricular function variables was observed between the tricuspid regurgitation classes.
Conclusions: For tricuspid regurgitation to be severe or torrential, both right atrial dilatation and leaflet tethering are needed. Interestingly, right cavities dilated progressively with tricuspid regurgitation severity, without joint degradation of right ventricular systolic function variables.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.acvd.2020.11.002 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
How to Reliably Measure Stroke Volume Index in Pulmonary Arterial Hypertension: A Comparison of Thermodilution, Direct and Indirect Fick, and Cardiac MRI.
Life (Basel)
January 2025
National Pulmonary Hypertension Service, Hammersmith Hospital, Imperial College NHS Trust, DuCane Road, London W12 0HS, UK.
Background: Stroke volume index (SVI) is an important prognostic parameter in pulmonary arterial hypertension (PAH). The direct Fick (DF) method represents the gold standard for measuring it. Indirect Fick (IF) and thermodilution (TD) are simpler and widely used alternatives.
View Article and Find Full Text PDFOutcomes and Predictors of Different Flow-Gradient Patterns of Aortic Stenosis Following Transcatheter Aortic Valve Replacement.
Am J Cardiol
January 2025
Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address:
This study sought to explore the clinical factors associated with classical low-flow low-gradient (C-LFLG) and normal-flow low-gradient (NFLG) aortic stenosis (AS) compared to high-gradient (HG) AS. We also compared clinical and echocardiographic outcomes after transcatheter aortic valve replacement (TAVR) across flow-gradient patterns. Patients with C-LFLG AS have a higher mortality rate after TAVR than those with HG AS.
View Article and Find Full Text PDFSystolic Flow Reversal Observed in the Superior Vena Cava Doppler Waveform Due to Severe Tricuspid Regurgitation: An Unreported Sign.
Ann Card Anaesth
January 2025
Division of Cardiothoracic and Vascular Anesthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Assessment of Right Ventricle Function in Patients with Mitral Repair: Case Series.
Ann Card Anaesth
January 2025
Department of Anaesthesiology and Intensive Care Medicine, Leipzig Heart Center, Leipzig, Germany.
Objectives: We aim to assess right ventricular function in patients undergoing mitral valve repair using trans-esophageal echocardiography, focusing on the predictive value of right ventricular longitudinal strain compared to other echocardiographic measures.
Design: Retrospective analysis.
Setting: Toronto General Hospital.
Ghostly intrusion on a frightful Halloween night: a case report of dual valve endocarditis.
Monaldi Arch Chest Dis
January 2025
Cardiology Department, Local Health Unit of Alto Ave, Guimarães.
Multivalvular endocarditis (MVE) is an uncommon presentation and mostly involves mitral and aortic valves. Here, we present a case of an MVE with an unusual and bizarre presentation on a Halloween night with a massive degree of valve destruction and right- and left-side involvement requiring emergent surgery. A 51-year-old male patient with intravenous drug usage presented with anorexia, fever, and dyspnea, rapidly progressing to septic shock with multiorgan dysfunction.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!