A Diamond in the Rough: IgA-Seq Signatures Stratify New Onset IBD.

Cell Host Microbe

Division of Gastroenterology and Hepatology, Department of Medicine, Jill Roberts Institute for Research in IBD, Jill Roberts Center for IBD, Weill Cornell Medicine, New York, NY, USA. Electronic address:

Published: January 2021

Intestinal immunoglobulin (Ig)A binds to distinct commensals and pathobionts, but do these IgA-coated bacterial communities define clinical characteristics of inflammatory disease? In this issue of Cell Host & Microbe, Shapiro et al. comprehensively analyze IgA-coated bacteria in new onset inflammatory bowel disease (IBD), revealing their potential in guiding precision therapy and diagnostic stratification.

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Source
http://dx.doi.org/10.1016/j.chom.2020.12.014DOI Listing

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