The instantaneous frequency (IF) image is proposed in this work. It is obtained by the differentiation of the instantaneous phase (IP) image, which in turn is calculated by replacing the amplitude information with the IP in the delay-and-sum beamforming. The IP image is a coherence factor that reduces artifacts and sidelobes influence, and it will be shown that the IF image will keep these same positive characteristics. In amplitude images the reflector representation level varies according to the experimental conditions, even using time-gain compensation. In IP images, the reflector is represented by a - π to π rad variation. An important feature of the IF image is that a reflector is represented by a constant level that is determined by the central frequency of the signal. Farther reflectors are represented with similar magnitudes as closer ones, being less influenced by distance than IP images and resulting in better contrast. Amplitude, IP, and IF images are obtained from point spread function simulations and a medical phantom in different experimental cases: vertical distances, contrast reflectors, axial and lateral separation, and a sparse array. The improper choice of dynamic range can result in low contrast or nondetection of a reflector. For the IF image, the dynamic range is determined by the central frequency of the signal and the zero-mean Gaussian distribution of the IF of noise. The IF image can be used to improve reflector detection, as additional information to assist the interpretation of pixels intensities in conventional amplitude images, or as a new coherence factor.
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http://dx.doi.org/10.1109/TUFFC.2021.3051496 | DOI Listing |
Acta Neurochir (Wien)
January 2025
Department of Neurosurgery and Department of Neuroscience, Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment, Xiamen Key Laboratory of Brain Center, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Purpose: To investigate the technique for dorsal median sulcus (DMS) mapping and assess its application value in preserving dorsal columnn (DC) function during intramedullary space occupying surgery based on a single-center experience.
Methods: A retrospective analysis was conducted on 41 cases of intramedullary spinal cord tumor admitted to the Department of Neurosurgery at the First Affiliated Hospital of Xiamen University from March 2017 to August 2023. All included cases underwent intraoperative electrophysiological monitoring, and were divided into a study group (n = 18) and a control group (n = 23), based on whether DMS mapping technique was utilized.
Anal Chem
January 2025
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Ligand binding to membrane proteins initiates numerous therapeutic processes. Surface plasmon resonance (SPR), a popular method for analyzing molecular interactions, has emerged as a promising tool for in situ determination of membrane protein binding kinetics owing to its label-free detection, high surface sensitivity, and resistance to intracellular interference. However, the excitation of SPR relies on noble metal films, typically gold, which are biologically incompatible and can cause fluorescence quenching.
View Article and Find Full Text PDFAnn Clin Transl Neurol
January 2025
Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.
Objective: To characterize structural integrity of the lumbosacral enlargement and conus medullaris within one month after spinal cord injury (SCI).
Methods: Lumbosacral cord MRI data were acquired in patients with sudden onset (<7 days) SCI at the cervical or thoracic level approximately one month after injury and in healthy controls. Tissue integrity and loss were evaluated through diffusion tensor (DTI) and T2*-weighted imaging (cross-sectional area [CSA] measurements).
Acta Bioeng Biomech
September 2024
Xinjiang University, China.
: The purpose of this study was to investigate dynamic responses of Lenke1B+ spines of adolescent scoliosis patients to different frequencies. : Modal analysis, harmonic response analysis and transient dynamics of a full spine model inverted by the finite element method using Abaqus. : The first-order axial resonance frequency of 4.
View Article and Find Full Text PDFBrain Struct Funct
January 2025
Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China.
A significant proportion of patients who have recovered from COVID-19 suffer from persistent symptoms, referred to as "post-acute sequelae of SARS-CoV-2 infection (PASC)". Abnormal brain intrinsic activity has been observed in PASC patients, but the patterns of frequency-dependent intrinsic activity in the PASC and non-PASC (recovered COVID-19 patients without persistent symptoms) groups and their association with neuropsychiatric sequelae remain unclear in PASC. Twenty-nine PASC patients, 27 non-PASC subjects, and 31 healthy controls (HCs) were recruited.
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