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Amlodipine-induced gingival hyperplasia in a Nepalese patient experiencing high dosages: a case report.
Ann Med Surg (Lond)
November 2024
Kathmandu University School of Medical Sciences, Dhulikhel, Kavre.
Introduction And Importance: Amlodipine is a third-generation calcium channel blocker used in the treatment of hypertension. One of the side effects associated with amlodipine is gingival hyperplasia mostly occurring at a higher dose (10 mg). There are very few cases of gingival hyperplasia associated with amlodipine at a lower dose (5 mg) or short-term administration.
View Article and Find Full Text PDFEffect of Co-Administration of Curcumin with Amlodipine in Hypertension.
Nutrients
August 2021
Department of Herbal Pharmacology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Curcumin, a curcuminoid known as the main bioactive compound of turmeric, is used in foods, cosmetics, and pharmaceutical products. Amlodipine is a general antihypertensive drug used in combination with various other antihypertensive agents. To date, no studies have examined the effects of the co-administration of amlodipine with curcumin.
View Article and Find Full Text PDFAmlodipine-induced generalized fixed drug eruption clinically mimicking mycosis fungoides.
Dermatol Ther
March 2021
Department of Pathology, Manisa, Turkey.
Effects of third-generation β-blockers, atenolol or amlodipine on blood pressure variability and target organ damage in spontaneously hypertensive rats.
J Hypertens
March 2020
Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Farmacología.
Background: β-blockers are no longer considered as first-line antihypertensive drugs due to their lower cardioprotection.
Method: Considering the differences in the pharmacological properties of β-blockers, the present work compared the effects of third-generation β-blockers - carvedilol and nebivolol - with a first-line agent - amlodipine - on hemodynamic parameters, including short-term blood pressure variability (BPV), and their ability to prevent target organ damage in spontaneously hypertensive rats (SHR). SHR rats were orally treated with carvedilol, nebivolol, atenolol, amlodipine or vehicle for 8 weeks.
Selective uveal melanoma inhibition with calcium channel blockade.
Int J Oncol
November 2019
Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114-2605, USA.
Uveal malignant melanoma (UMM), the most common primary adult intraocular tumor with a marked metastatic potential, is genetically unique and has unfortunately had few treatment breakthroughs. In this study, we subjected a UMM cell line to high‑throughput library screening with 1,018 FDA‑approved compounds to identify potential UMM‑selective cytotoxic agents. Amlodipine, a dihydropyridine calcium channel blocker (CCB), ranked no.
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