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Genomic imprinting: the influence of differential methylation in the two sexes.
Exp Biol Med (Maywood)
February 2010
Biological Targets Inc, PO Box 1529, Pilot Point, TX 76258, USA.
Genomic imprinting is an epigenetic form of gene regulation that entails differential sex-specific methylation of the alleles of a gene. Such methylation distinguishes male and female genomes and is inherited in a parent-of-origin-specific manner. Sex-specific imprints are established in the germline during gametogenesis and remain intact throughout embryonic and postnatal development.
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