AI Article Synopsis
- - MA methyltransferases are key enzymes that add a methyl group to RNA, impacting various life processes and have gained significant research interest.
- - The review outlines the roles of these enzymes in important biological functions like cell growth, nerve development, and immune response, highlighting their broad significance in health.
- - It also points out ongoing challenges in this research area and suggests that mA methyltransferases could become potential targets for new disease prevention and treatment strategies.
Article Abstract
MA methyltransferases, acting as a writer in N6-methyladenosine, have attracted wide attention due to their dynamic regulation of life processes. In this review, we first briefly introduce the individual components of mA methyltransferases and explain their close connections to each other. Then, we concentrate on the extensive biological functions of mA methyltransferases, which include cell growth, nerve development, osteogenic differentiation, metabolism, cardiovascular system homeostasis, infection and immunity, and tumour progression. We summarize the currently unresolved problems in this research field and propose expectations for mA methyltransferases as novel targets for preventive and curative strategies for disease treatment in the future.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798219 | PMC |
| http://dx.doi.org/10.1186/s13578-020-00513-0 | DOI Listing |
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