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What's Going On With Me and How Can I Better Manage My Health? The Potential of GPT-4 to Transform Discharge Letters Into Patient-Centered Letters to Enhance Patient Safety: Prospective, Exploratory Study.
J Med Internet Res
January 2025
Department of Medical Strategy, Process and Quality Management, University Hospital Tübingen, Tübingen, Germany.
Background: For hospitalized patients, the discharge letter serves as a crucial source of medical information, outlining important discharge instructions and health management tasks. However, these letters are often written in professional jargon, making them difficult for patients with limited medical knowledge to understand. Large language models, such as GPT, have the potential to transform these discharge summaries into patient-friendly letters, improving accessibility and understanding.
View Article and Find Full Text PDFReal-world evidence in extensive disease small cell lung cancer: The missing piece of the puzzle.
Crit Rev Oncol Hematol
January 2025
Section of Innovation Biomedicine - Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona, Italy. Electronic address:
Small cell lung cancer (SCLC) is a highly aggressive disease, often diagnosed at an advanced stage and with limited treatment options. In recent years, immunotherapy has been approved in combination with chemotherapy in the first line setting of extensive stage disease (ES-SCLC). However, only 10-15 % of patients with ES-SCLC treated with chemoimmunotherapy (CT-IO) experience a long-term benefit.
View Article and Find Full Text PDFTransient chaos and periodic structures in a model of neuronal early afterdepolarization.
Chaos
January 2025
Departamento de Física, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Santa Catarina, Brazil.
The presence of chaos is ubiquitous in mathematical models of neuroscience. In experimental neural systems, chaos was convincingly demonstrated in membranes, neurons, and small networks. However, its effects on the brain have long been debated.
View Article and Find Full Text PDFAnterior Segment Optical Coherence Tomography Evaluation of a Dexamethasone Intravitreal Implant in the Crystalline Lens: A Case Report.
Int Med Case Rep J
January 2025
Department of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.
Purpose: Ozurdex is a dexamethasone intravitreal implant approved for the treatment of macular edema secondary to branch or central retinal vein occlusion, non-infectious uveitis affecting the posterior segment of the eye, and diabetic macular edema.
Patients And Methods: We report a case of an accidental injection of the implant into the crystalline lens, successfully managed by surgery afterwards. The case description is supported by Anterior Segment Optical Coherence Tomography (AS-OCT) images.
The missing piece: The clinical translation of precision diabetes medicine requires precision mental health care: A call to action from the international PsychoSocial Aspects of Diabetes (PSAD) Study Group.
Diabet Med
January 2025
Department of Psychology, University of Southern Denmark, Odense, Denmark.
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