Few interventions have targeted resilience resources in people living with HIV (PLWH). We tested the acceptability of an existing resilience intervention in middle-age and older PLWH. Fourteen PLWH attended one 3-hr group session, which included videos, quizzes, and written activities. Participants provided quantitative and qualitative feedback. The mean acceptability rating was 8.71 (1.27) on a 10-point scale. A majority of participants reported that the intervention was an appropriate length; that it improved their resilience, mood, and ability to manage HIV; and that they would likely continue using the tools. Average content retention accuracy was 75% (12.66). Qualitative feedback suggested addressing HIV-specific stressors, including disclosure concerns, stigma, health concerns, and treatment adherence. The resilience intervention was deemed highly acceptable among older PLWH. Uptake may increase by addressing HIV-specific stressors and improving comprehensibility. Future research should further refine and test the efficacy of a modified version of the intervention.
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http://dx.doi.org/10.1097/JNC.0000000000000229 | DOI Listing |
Sci Rep
December 2024
Imperial College London, London, UK.
Accurate estimation of the soil resilient modulus (M) is essential for designing and monitoring pavements. However, experimental methods tend to be time-consuming and costly; regression equations and constitutive models usually have limited applications, while the predictive accuracy of some machine learning studies still has room for improvement. To forecast M efficiently and accurately, a new model named black-winged kite algorithm-extreme gradient boosting (BKA-XGBOOST) is proposed.
View Article and Find Full Text PDFJ Child Adolesc Ment Health
December 2024
Department of Educational Psychology, University of Pretoria, Pretoria, South Africa.
Resilience is central to young children's healthy and happy development. The Child and Youth Resilience Measure (CYRM-R) has been widely used in several countries. However, its construct validity among young children in rural South Africa has not been examined.
View Article and Find Full Text PDFJ Community Psychol
January 2025
Nursing Faculty, Public Health Nursing Department, Atatürk University, Yakutiye Erzurum, Turkey.
This study aimed to investigate the resilience, stress levels, coping styles, and the impact of related factors among nurses working in primary healthcare during the COVID-19 pandemic. Designed as a cross-sectional study, the research included 86 volunteer nurses employed in primary healthcare institutions in Bitlis provincial center and its districts in Turkey. Data were collected between March and June 2022 using a sociodemographic information form, the Resilience Scale for Adults, and the Ways of Coping Questionnaire.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Introduction: Alzheimer's disease (AD), primary age-related tauopathy (PART), and chronic traumatic encephalopathy (CTE) all feature hyperphosphorylated tau (p-tau)-immunoreactive neurofibrillary degeneration, but differ in neuroanatomical distribution and progression of neurofibrillary degeneration and amyloid beta (Aβ) deposition.
Methods: We used Nanostring GeoMx Digital Spatial Profiling to compare the expression of 70 proteins in neurofibrillary tangle (NFT)-bearing and non-NFT-bearing neurons in hippocampal CA1, CA2, and CA4 subregions and entorhinal cortex of cases with autopsy-confirmed AD (n = 8), PART (n = 7), and CTE (n = 5).
Results: There were numerous subregion-specific differences related to Aβ processing, autophagy/proteostasis, inflammation, gliosis, oxidative stress, neuronal/synaptic integrity, and p-tau epitopes among these different disorders.
Alzheimers Dement
December 2024
Department of Neuroregeneration, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Introduction: Some individuals show intact cognition despite the presence of neuropathological hallmarks of Alzheimer's disease (AD). The plasticity of parvalbumin (PV)-containing interneurons might contribute to resilience. Perineuronal nets (PNNs), that is, extracellular matrix structures around neurons, modulate PV neuron function.
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